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Tg(Prnp-PARK2)196Kfw
Transgene Detail
Summary
Symbol: Tg(Prnp-PARK2)196Kfw
Name: transgene insertion 196, Konstanze Winklhofer
MGI ID: MGI:5705575
Synonyms: h-parkin
Transgene: Tg(Prnp-PARK2)196Kfw  Location: unknown  
Alliance: Tg(Prnp-PARK2)196Kfw page
Transgene
origin
Strain of Origin:  FVB/NJ
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Prnp-PARK2)196Kfw expresses 1 gene
 
Mutation detailsThe transgenic construct contains 1398 bp of the human parkin ORF (PARK2) under control of the mouse prion promoter (Prnp). (J:222420)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:222420 Meka DP, et al., Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration. J Clin Invest. 2015 May;125(5):1873-85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory