Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pelotm2Imad
Name:	pelota mRNA surveillance and ribosome rescue factor; targeted mutation 1, Ibrahim M Adham
MGI ID:	MGI:5705245
Synonyms:	PeloF
Gene:	Pelo  Location: Chr13:115224891-115226694 bp, - strand  Genetic Position: Chr13, 64.61 cM
Alliance:	Pelotm2Imad page

Germline Transmission:	Earliest citation of germline transmission: J:228122
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: One loxP site was inserted into intron 1 and a second loxP site was inserted into the 3-prime flanking region of this gene to create a conditional ready allele in which cre mediated exision will remove exons 2 and 3, which are the coding exons. (J:228122)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pelo Mutation:	14 strains or lines available

Original:	J:228122 Nyamsuren G, et al., Pelota regulates the development of extraembryonic endoderm through activation of bone morphogenetic protein (BMP) signaling. Stem Cell Res. 2014 Jul;13(1):61-74
All:	5 reference(s)