Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cidectm1.1Gonz
Name:	cell death-inducing DFFA-like effector c; targeted mutation 1.1, Frank Gonzalez
MGI ID:	MGI:5699259
Synonyms:	Fsp27F
Gene:	Cidec  Location: Chr6:113401595-113412721 bp, - strand  Genetic Position: Chr6, 52.76 cM, cytoband E3
Alliance:	Cidectm1.1Gonz page

Germline Transmission:	Earliest citation of germline transmission: J:226899
Parent Cell Line:	v6.4 (ES Cell)
Strain of Origin:	(C57BL/6J x 129S4/SvJae)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The targeting vector contains a loxP site upstream of exon 2 and an FRT-flanked neomycin selection cassette followed by a second loxP site downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 2 and 3 floxed. (J:226899)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cidec Mutation:	15 strains or lines available

Original:	J:226899 Tanaka N, et al., Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice. J Biol Chem. 2015 Jan 30;290(5):3092-105
All:	3 reference(s)