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Gene Expression Data
Assay Details
Assay
Reference: J:54164 Turnley AM, et al., Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J Neurochem. 1999 Apr;72(4):1707-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5698426
Gene symbol: Prkab2
Gene name: protein kinase, AMP-activated, beta 2 non-catalytic subunit
Results
Specimen 2H: postnatal day 23 (more )
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Present Regionally restricted 2H Cytoplasmic expression in pyramidal cells.
Specimen 3F: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Regionally restricted 3F Highest expression in cytoplasm of Purkinje cells, including their dendrites.
TS28: cerebellum granule cell layer Weak Regionally restricted 3F Much lower levels of expression in cytoplasm of granule cells.
Specimen 4F: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Absent 4F
Specimen 5D: postnatal day 23 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present Regionally restricted 5D Expression in some astrocytes. No expression in motor neurons.
Specimen Table 1: postnatal (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted Expression in neurons. No expression in astrocytes.
TS28: hippocampus Present Regionally restricted Not detectable to medium expression in activated astrocytes. Not detectable to low expression in astrocytes.
TS28: hippocampus pyramidal cell layer Present Regionally restricted Expression in pyramidal cells.
TS28: cerebellum Purkinje cell layer Very strong Regionally restricted Very high expression in Purkinje cells.
TS28: cerebellum granule cell layer Weak Regionally restricted Low expression in granule cells.
TS28: cerebellum Present Regionally restricted Not detectable to low expression in astrocytes.
TS28: spinal cord Present Regionally restricted Barely detectable to high expression in motor neurons. Not detectable to medium expression in astrocytes.
TS28: facial nucleus Absent No expression in motor neurons.
TS28: main olfactory bulb Absent No expression in mitral, granule or periglomerular cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory