Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Zbtb46tm2Mnz
Name:	zinc finger and BTB domain containing 46; targeted mutation 2, Michel C Nussenzweig
MGI ID:	MGI:5697173
Synonyms:	zDClox
Gene:	Zbtb46  Location: Chr2:181029555-181101219 bp, - strand  Genetic Position: Chr2, 103.63 cM, cytoband H4
Alliance:	Zbtb46tm2Mnz page

Germline Transmission:	Earliest citation of germline transmission: J:191314
Parent Cell Line:	CY2.4 (ES Cell)
Strain of Origin:	B6(Cg)-Tyrc-2J

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 2 of the mouse Zbtb46 gene, encoding the translational start site and the BTB protein-binding domain, is flanked by loxP sites. (J:191314)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zbtb46 Mutation:	36 strains or lines available

Original:	J:191314 Meredith MM, et al., Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state. J Exp Med. 2012 Aug 27;209(9):1583-93
All:	1 reference(s)