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Gene Expression Data
Assay Details
Assay
Reference: J:54003 Gamer LW, et al., A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos. Dev Biol. 1999 Apr 1;208(1):222-32
Assay type: RNA in situ
MGI Accession ID: MGI:5691598
Gene symbol: Gdf11
Gene name: growth differentiation factor 11
Probe: BMP-11 probe
Probe preparation: Antisense RNA
Results
Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Absent

Specimen 2A: embryonic day 9.5 (more )
Note: lateral view
Structure Level Pattern Image Note
TS15: tail Weak Regionally restricted 2A Expression at the tip.
TS15: forelimb bud Absent 2A

Specimen 2B: embryonic day 9.75-10.0 (more )
Note: lateral view
Structure Level Pattern Image Note
TS15: tail Strong 2B
TS15: forelimb bud Present Regionally restricted 2B Expression in the distal portion.
TS15: forelimb bud mesenchyme Present 2B Strongest staining in the posterior mesenchyme.

Specimen 2C: embryonic day 10.5 (more )
Note: lateral view
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2C Expression is present in the neural tube.
TS17: dorsal root ganglion Present 2C
TS17: forelimb bud mesenchyme Strong Regionally restricted 2C Expression is distal and posterior.
TS17: hindlimb bud Strong Regionally restricted 2C Expression is distal and posterior.
TS17: forelimb bud apical ectodermal ridge Absent 2C
TS17: tail Strong 2C Expression is in the caudal-most region.

Specimen 2D: embryonic day 11.0 (more )
Note: lateral view
Structure Level Pattern Image Note
TS18: tail Strong Regionally restricted 2D Expression is in the caudal-most region.
TS18: forelimb bud Strong Regionally restricted 2D , 2F Expression is in distal and posterior regions.
TS18: forelimb bud apical ectodermal ridge Absent 2F , 2D
TS18: hindlimb bud Strong Regionally restricted 2D Expression is in the distal limb.
TS18: dorsal root ganglion Present Non-Uniform 2D Expression is stronger in the most caudal (most newly-differentiated) ganglia.

Specimen 2E: embryonic day 11.5 (more )
Note: lateral view
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present Non-Uniform 2E Expression is stronger in the most caudal (most newly-differentiated) ganglia.
TS19: forelimb bud mesenchyme Present Regionally restricted 2E , 2G Expression is present in the mesenchyme surrounding the precartilaginous condensations.
TS19: hindlimb bud mesenchyme Present Regionally restricted 2E Expression is present in the mesenchyme surrounding the precartilaginous condensations.

Specimen 2H: embryonic day 12.5 (more )
Note: lateral view
Structure Level Pattern Image Note
TS20: tail Strong Regionally restricted 2H Expression is in the caudal-most region.
TS20: dorsal root ganglion Present Non-Uniform 2H Expression is stronger in the most caudal (most newly-differentiated) ganglia.
TS20: forelimb mesenchyme Present Regionally restricted 2H Expression is seen between the skeletal elements.
TS20: hindlimb mesenchyme Present Regionally restricted 2H Expression is seen between the skeletal elements.
TS20: foot Present Regionally restricted 2H Expression is present at digit tips.
TS20: hand Present Regionally restricted 2H Expression is present at digit tips.

Specimen 2I: embryonic day 11.0 (more )
Note: transverse section
Structure Level Pattern Image Note
TS18: tail future spinal cord Present 2I Expression in the neuroepithelium and closing neural tube.
TS18: tail paraxial mesenchyme Present 2I Expression in the dorsal-lateral mesenchyme.

Specimen 2J: embryonic day 11.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 2J Expression present in the dorsal-lateral region. No expression is seen in the ventral neural tube.
TS19: neural tube mantle layer Present Regionally restricted 2J Expression localized to the outer layer.
TS19: neural tube floor plate Absent 2J
TS19: neural tube roof plate Absent 2J
TS19: dorsal root ganglion Present 2J

Specimen not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Present
TS22: spinal cord Present

Specimen not shown: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: dorsal root ganglion Present
TS24: spinal cord Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory