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Gene Expression Data
Assay Details
Assay
Reference: J:96501 Sasaki T, et al., LEF1 is a critical epithelial survival factor during tooth morphogenesis. Dev Biol. 2005 Feb 1;278(1):130-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5661459
Gene symbol: Ccna1
Gene name: cyclin A1
Antibody: anti-cyclin A
Detection system: Secondary antibody
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 6I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Present 6I Expressed in dental epithelium.
TS21: tooth mesenchyme Present Regionally restricted 6I Expressed in the cranial neural crest-derived mesenchyme.
Specimen 6J: embryonic day 13.5; Lef1tm1Rug/Lef1tm1Rug (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Present 6J Normal expression as in wild-type.
TS21: tooth mesenchyme Present 6J Normal expression as in wild-type.
Specimen 6K: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tooth epithelium Present Regionally restricted 6K Expressed in dental epithelium, except the enamel knot.
TS22: tooth mesenchyme Present Regionally restricted 6K Expressed in the cranial neural crest-derived mesenchyme.
TS22: enamel knot Absent 6K
Specimen 6L: embryonic day 14.5; Lef1tm1Rug/Lef1tm1Rug (more )
Structure Level Pattern Image Note
TS22: tooth epithelium Present 6L Normal expression as in wild-type.
TS22: tooth mesenchyme Present 6L Normal expression as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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