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Gene Expression Data
Assay Details
Assay
Reference: J:109037 Kim HJ, et al., WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination. J Neurosci. 2006 May 24;26(21):5849-59
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5661368
Gene symbol: Scn8a
Gene name: sodium channel, voltage-gated, type VIII, alpha
Antibody: Anti-Nav1.6
Results
Specimen 5C,D WT: postnatal day 21 (more )
Note: Double labeled: red - Scn8a; green - Cntnap1 (assay MGI:5661364).
Structure Level Pattern Image Note
TS28: optic nerve Present Regionally restricted 5D WT , 5C WT Expression was detected in the nodes of the optic nerve.

Specimen 5C,D Wave1-/-: postnatal day 21; Wasf1Gt(VICTR37)1Kwak/Wasf1Gt(VICTR37)1Kwak (more )
Note: Double labeled: red - Scn8a; green - Cntnap1 (assay MGI:5661364).
Structure Level Pattern Image Note
TS28: optic nerve Weak Regionally restricted 5D Wave1-/- , 5C Wave1-/- Expression was detected in the nodes. The fluorescence intensity was less than observed in wild type.

Specimen 5E,F WT: postnatal day 21 (more )
Note: Double labeled: red - Scn8a; green - Kcna1 (assay MGI:5661365).
Structure Level Pattern Image Note
TS28: optic nerve Present Regionally restricted 5E WT , 5F WT Expression was detected in the nodes of the optic nerve.

Specimen 5E,F Wave1-/-: postnatal day 21; Wasf1Gt(VICTR37)1Kwak/Wasf1Gt(VICTR37)1Kwak (more )
Note: Double labeled: red - Scn8a; green - Kcna1 (assay MGI:5661365).
Structure Level Pattern Image Note
TS28: optic nerve Weak Regionally restricted 5F Wave1-/- , 5E Wave1-/- Expression was detected in the nodes. The fluorescence intensity was less than observed in wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory