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Gene Expression Data
Assay Details
Assay
Reference: J:73841 Mailhos C, et al., Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation. 2001 Dec;69(2-3):135-44
Assay type: RNA in situ
MGI Accession ID: MGI:5646239
Gene symbol: Dll4
Gene name: delta like canonical Notch ligand 4
Probe: Dll4 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: Reichert's membrane Present 1A
TS11: extraembryonic component Present 1A
TS11: trophectoderm Present 1A
TS11: embryo Absent 1A
Specimen 1C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Present Regionally restricted 1C Expression is in the endothelium of the axial dorsal aorta.
TS13: heart Present 1C
TS13: umbilical artery Present 1C
TS13: venous system Absent 1C
Specimen 1E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch artery Present 1E
TS15: dorsal aorta Present 1E
TS15: heart Present 1E
TS15: umbilical artery Present 1E
TS15: blood vessel Present Regionally restricted 1E Expression is in intersomitic vessels.
TS15: arterial system Present Regionally restricted 1E Expression is in major arterial vessels.
Specimen 1G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 1G Expression is in the yolk sac artery and in a subset of vessels.
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal aorta Present Regionally restricted 2A Expression is in the endothelium.
TS19: anterior cardinal vein Absent 2A
Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal aorta Present Regionally restricted 2B Expression is in a subset of endothelial cells within the vessel and in cells directly adjacent to the lumen.
Specimen 2C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thymus Present 2C
TS24: arterial system Present Regionally restricted 2C Absent in endothelium of major arterial vessels.
TS24: blood vessel Present Regionally restricted 2C Expression is in endothelium of small vessels and capillaries.
Specimen 2D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: arterial system Present Regionally restricted 2D Expression is in endothelium of small vessels and capillaries, and is downregulated in larger vessels.
Specimen 2F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present 2F
Specimen 4A,A',B: postnatal adult (more )
Note: Virgin mouse ovary. (A/A') Brightfield/darkfield pair. The are boxed in (A') is magnified in (B).
Structure Level Pattern Image Note
TS28: ovary Absent 4B , 4A , 4A'
Specimen 4C,C',D: postnatal adult (more )
Note: Ovulating female. (C/C') Brightfield/darkfield pair. The are boxed in (C') is magnified in (D).
Structure Level Pattern Image Note
TS28: developing vasculature of ovary Strong 4D , 4C' , 4C Expression is in the capillaries and small vessels of the growing vessels, absent in neighboring blood vessels.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory