Tg(Vav1-EIF2AK2*K296R)1Wsmay
Transgene Detail
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| Symbol: |
Tg(Vav1-EIF2AK2*K296R)1Wsmay |
| Name: |
transgene insertion 1, W May |
| MGI ID: |
MGI:5646211 |
| Synonyms: |
TgDNPKR |
| Transgene: |
Tg(Vav1-EIF2AK2*K296R)1Wsmay Location: unknown
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| Alliance: |
Tg(Vav1-EIF2AK2*K296R)1Wsmay page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Vav1-EIF2AK2*K296R)1Wsmay expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
EIF2AK2 (5610) |
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The cDNA carries the K296R mutation. |
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Mutation details: The transgene consists of mouse vav 1 oncogene promoter/control regions directing expression of a catalytically-null/dominant-negative (K296R) mutant variant of human eukaryotic translation initiation factor 2-alpha kinase 2 cDNA sequence.
(J:196300)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:196300 Liu X, et al., PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells. Blood. 2013 Apr 25;121(17):3364-74 |
| All: |
1 reference(s) |
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Analysis Tools
