Tg(Vav1-EIF2AK2)#Wsmay
Transgene Detail
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| Symbol: |
Tg(Vav1-EIF2AK2)#Wsmay |
| Name: |
transgene insertion, W May |
| MGI ID: |
MGI:5646202 |
| Synonyms: |
TgPKR |
| Transgene: |
Tg(Vav1-EIF2AK2)#Wsmay Location: unknown
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| Alliance: |
Tg(Vav1-EIF2AK2)#Wsmay page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Vav1-EIF2AK2)#Wsmay expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
EIF2AK2 (5610) |
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Mutation details: The transgenic construct contains a mouse vav 1 oncogene promoter/control regions directing expression of a wildtype (catalytically-active) human eukaryotic translation initiation factor 2-alpha kinase 2 cDNA sequence (EIF2AK2). Three transgenic (TgPKR) founder lines were generated; all displaying the same phenotype and were used interchangeably.
(J:196300)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:196300 Liu X, et al., PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells. Blood. 2013 Apr 25;121(17):3364-74 |
| All: |
2 reference(s) |
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Analysis Tools
