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Tg(CD2-Il23r)2Cdon
Transgene Detail
Summary
Symbol: Tg(CD2-Il23r)2Cdon
Name: transgene insertion 2, Chen Dong
MGI ID: MGI:5642079
Synonyms: IL-23R Tg
Transgene: Tg(CD2-Il23r)2Cdon  Location: unknown  
Alliance: Tg(CD2-Il23r)2Cdon page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CD2-Il23r)2Cdon expresses 1 gene
 
Mutation detailsA transgenic vector was generated with interleukin 23 receptor (Il23r) cDNA, amplified from a T helper (Th) 17 cell pool, followed by polyadenylation signal (polyA), under control of a human CD2 promoter. This construct also contains the CD2 locus control region (LCR) to increase gene expression by preventing the down-modulation of the expressed gene. Line 2 was analyzed. (J:221933)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:221933 Peng J, et al., IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation. Cell Res. 2010 Jan;20(1):62-71
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory