Gene Expression Data
Assay Details
Assay
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Reference:
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J:175980
Mortensen AH, et al., Candidate genes for panhypopituitarism identified by gene expression profiling. Physiol Genomics. 2011 Oct 6;43(19):1105-16
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5641342
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Gene symbol:
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Otx2
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Gene name:
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orthodenticle homeobox 2
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Probe:
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Otx2 probe30
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Probe preparation:
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labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
3Aa:
embryonic day 10.5
(more )
Specimen
3Aa:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS17: diencephalon |
Present |
Regionally restricted |
3Aa
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Expression in ventral diencephalon.
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TS17: Rathke's pouch |
Present |
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3Aa
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Expression in invaginated oral ectoderm.
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Specimen
3Ac:
embryonic day 12.5
(more )
Specimen
3Ac:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS20: diencephalon |
Present |
Regionally restricted |
3Ac
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Expression persists in region of ventral diencephalon.
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Specimen
3Ad:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Prop1df/Prop1df
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: diencephalon |
Present |
Regionally restricted |
3Ad
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Expression in ventral diencephalon.
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Specimen
3Ae:
embryonic day 14.5
(more )
Specimen
3Ae:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3Af:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Prop1df/Prop1df
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3Ag:
embryonic day 16.5
(more )
Specimen
3Ag:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS24: diencephalon |
Absent |
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3Ag
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No expression in ventral diencephalon or any pituitary gland lobe.
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TS24: pituitary gland |
Absent |
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3Ag
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No expression in ventral diencephalon or any pituitary gland lobe.
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Specimen
3Ah:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Prop1df/Prop1df
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3Ai:
postnatal day 1
(more )
Specimen
3Ai:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS27: diencephalon |
Absent |
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3Ai
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No expression in ventral diencephalon or any pituitary gland lobe.
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TS27: pituitary gland |
Absent |
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3Ai
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No expression in ventral diencephalon or any pituitary gland lobe.
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Specimen
3Aj:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Prop1df/Prop1df
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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