Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Bap1em1Test
Name:	Brca1 associated protein 1; endonuclease-mediated mutation 1, Joseph R Testa
MGI ID:	MGI:5638884
Gene:	Bap1  Location: Chr14:30973407-30981901 bp, + strand  Genetic Position: Chr14, 19.09 cM
Alliance:	Bap1em1Test page

Strain of Origin:

FVB

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion     Zinc finger nuclease mediated targeted mutation deleted exons 6 and 7. (J:213725)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

List all tumor models in MMHCdb carrying Bap1em1Test

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bap1 Mutation:	37 strains or lines available

Original:	J:213725 Xu J, et al., Germline mutation of Bap1 accelerates development of asbestos-induced malignant mesothelioma. Cancer Res. 2014 Aug 15;74(16):4388-97
All:	2 reference(s)