Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mex3btm1.2Mbld
Name:	mex3 RNA binding family member B; targeted mutation 1.2, Marc Billaud
MGI ID:	MGI:5638674
Synonyms:	Mex3b-
Gene:	Mex3b  Location: Chr7:82516541-82520723 bp, + strand  Genetic Position: Chr7, 47.35 cM
Alliance:	Mex3btm1.2Mbld page

Germline Transmission:	Earliest citation of germline transmission: J:213588
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was floxed and a floxed neo cassette was inserted via homologous recombination. Cre mediated recombination removed exon 2 and the neo cassette. Molecular analyses confirmed the absence of mRNA and protein in both mouse embryonic fibroblasts (MEFs) and testis extracts from homozygous mutant mice. (J:213588)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mex3b Mutation:	19 strains or lines available

Original:	J:213588 Le Borgne M, et al., The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway. Development. 2014 May;141(10):2096-107
All:	1 reference(s)