Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Bmi1tm1.1Sjm
Name:	Bmi1 polycomb ring finger oncogene; targeted mutation 1.1, Sean J Morrison
MGI ID:	MGI:5638198
Synonyms:	Bmi1fl
Gene:	Bmi1  Location: Chr2:18681953-18691440 bp, + strand  Genetic Position: Chr2, 12.9 cM
Alliance:	Bmi1tm1.1Sjm page

Germline Transmission:	Earliest citation of germline transmission: J:213217
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site and an FRT flanked neo cassette were inserted upstream the first coding exon and a loxP site was inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:213217)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Bmi1 Mutation:	33 strains or lines available

Original:	J:213217 Mich JK, et al., Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. Elife. 2014;3:e02669
All:	4 reference(s)