Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Impdh2tm2Bmi
Name:	inosine monophosphate dehydrogenase 2; targeted mutation 2, Beverly S Mitchell
MGI ID:	MGI:5634346
Synonyms:	Impdh2loxP
Gene:	Impdh2  Location: Chr9:108437635-108442776 bp, + strand  Genetic Position: Chr9, 59.5 cM
Alliance:	Impdh2tm2Bmi page

Germline Transmission:	Earliest citation of germline transmission: J:225937
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: FRT/loxP sites are located between exons 1 and 2, and second loxP site located between exons 9 and 10. The selection cassette was removed. (J:225937)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Impdh2 Mutation:	40 strains or lines available

Original:	J:225937 Lake JI, et al., Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton. Dev Biol. 2016 Jan 1;409(1):152-165
All:	1 reference(s)