Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hamp2tm1Ddhf
Name:	hepcidin antimicrobial peptide 2; targeted mutation 1, Duygu Dee Harrison-Findik
MGI ID:	MGI:5634094
Synonyms:	Hamp1/2
Gene:	Hamp2  Location: Chr7:30621797-30623606 bp, - strand  Genetic Position: Chr7, 19.27 cM
Alliance:	Hamp2tm1Ddhf page

Germline Transmission:	Earliest citation of germline transmission: J:220227
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The targeting vector contains lox2272 (loxP variant) sites flanking exons 2 and 3 of the gene, and variant flpe recognition sequences flanking a PGK-HYGRO cassette downstream of the first lox2272 site. This allele was generated in ES cells containing Hamptm1Ddhf on the same chromosome. (J:220227)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hamp2 Mutation:	7 strains or lines available

Original:	J:220227 Lu S, et al., Inductively coupled mass spectrometry analysis of biometals in conditional Hamp1 and Hamp1 and Hamp2 transgenic mouse models. Transgenic Res. 2015 Aug;24(4):765-73
All:	1 reference(s)