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Tg(Ucp1-luc2,-tdTomato)1Kajim
Transgene Detail
Summary
Symbol: Tg(Ucp1-luc2,-tdTomato)1Kajim
Name: transgene insertion 1, Shingo Kajimura
MGI ID: MGI:5619504
Synonyms: Ucp1-luciferase
Transgene: Tg(Ucp1-luc2,-tdTomato)1Kajim  Location: unknown  
Alliance: Tg(Ucp1-luc2,-tdTomato)1Kajim page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation details: The 98.6 kb mouse bacterial artificial chromosome (BAC) bMQ353d13 containing the entire Ucp1 gene, was modified by inserting a a luciferase2-T2A-tdTomato reporter cassette into Ucp1 exon 1 at the initiation codon. Luciferase2 is a modified version of firefly luciferase. (J:218083)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
The transgene is thought to have inserted into the Y chromosome as only male mice are carriers.
References
Original:  J:218083 Galmozzi A, et al., ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue. Cell Rep. 2014 Dec 11;9(5):1584-93
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory