Map1lc3a Western blot Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:203842 He C, et al., Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism. Cell. 2013 Aug 29;154(5):1085-99
Assay type:	Western blot
MGI Accession ID:	MGI:5615643
Gene symbol:	Map1lc3a
Gene name:	microtubule-associated protein 1 light chain 3 alpha

Antibody:	anti-LC3
Detection system:	Secondary antibody

Results

Image: S6F LC3-I LC3-II

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
beclin 2 +/+ 1	P adult	TS28: brain	Present	involves: C57BL/6J		Male
beclin 2 +/+ 2	P adult	TS28: brain	Present	involves: C57BL/6J		Male
beclin 2 +/+ 3	P adult	TS28: brain	Present	involves: C57BL/6J		Male
beclin 2 +/+ 4	P adult	TS28: brain	Present	involves: C57BL/6J		Male
beclin 2 +/+ 5	P adult	TS28: brain	Present	involves: C57BL/6J		Male
beclin 2 +/+ 6	P adult	TS28: brain	Present	involves: C57BL/6J		Male
beclin 2 +/- 1	P adult	TS28: brain	Present (a)	B6.Cg-Becn2^tm1.1Blev	Becn2^tm1.1Blev/Becn2⁺	Male
beclin 2 +/- 2	P adult	TS28: brain	Present (a)	B6.Cg-Becn2^tm1.1Blev	Becn2^tm1.1Blev/Becn2⁺	Male
beclin 2 +/- 3	P adult	TS28: brain	Present (a)	B6.Cg-Becn2^tm1.1Blev	Becn2^tm1.1Blev/Becn2⁺	Male
beclin 2 +/- 4	P adult	TS28: brain	Present (a)	B6.Cg-Becn2^tm1.1Blev	Becn2^tm1.1Blev/Becn2⁺	Male
beclin 2 +/- 5	P adult	TS28: brain	Present (a)	B6.Cg-Becn2^tm1.1Blev	Becn2^tm1.1Blev/Becn2⁺	Male
beclin 2 +/- 6	P adult	TS28: brain	Present (a)	B6.Cg-Becn2^tm1.1Blev	Becn2^tm1.1Blev/Becn2⁺	Male

Notes:
(a) Elevated levels of total LC3 and decreased conversion of LC3-I to LC3-II in beclin 2 +/- mice compared to wild-type littermates.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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