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Gene Expression Data
Assay Details
Assay
Reference: J:37702 Nadeau A, et al., In situ hybridization analysis of ZPK gene expression during murine embryogenesis. J Histochem Cytochem. 1997 Jan;45(1):107-18
Assay type: RNA in situ
MGI Accession ID: MGI:5613118
Gene symbol: Map3k12
Gene name: mitogen-activated protein kinase kinase kinase 12
Probe: Zpk cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Strong 2A
TS25: intestine epithelium Strong 2A
TS25: pancreas epithelium Strong 2A
TS25: spinal ganglion Strong 2A
TS25: metanephros Strong Regionally restricted 2A Expression is in the epithelium.
TS25: skin Strong Graded 2A Highest levels are posteriorly and caudally.
TS25: liver Absent 2A
TS25: lung epithelium Absent 2A

Specimen 3A: embryonic day 11.5 (more )
Note: B is a higher magnification of A.
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 3B , 3A Expression is in a small group of neuronal cells distributed throughout the telencephalon.

Specimen 3D: embryonic day 15.5 (more )
Note: E is a higher magnification of D.
Structure Level Pattern Image Note
TS23: telencephalon marginal layer Present 3D , 3E

Specimen 3G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal ganglion Strong 3G
TS23: peripheral nerve Absent 3G

Specimen 3H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: spinal ganglion Strong 3H
TS25: peripheral nerve Absent 3H

Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: epidermis Absent 4A

Specimen 4B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epidermis Present Regionally restricted 4B Expression is in the stratum granulosum, absent in the stratum germinativum.
TS23: hair follicle Present 4B
TS23: dermis Absent 4B

Specimen 4C: embryonic day 17.5 (more )
Note: D is a higher magnification of C.
Structure Level Pattern Image Note
TS25: epidermis Strong Regionally restricted 4D , 4C Expression is in the stratum granulosum, absent in the stratum germinativum.
TS25: hair follicle Present 4C , 4D
TS25: dermis Absent 4D , 4C

Specimen 5A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: vibrissa follicle Present Regionally restricted 5A Expression is in one part of the inner root sheath, absent in outer root sheath or in follicle cortical cells.

Specimen 5B: embryonic day 17.5 (more )
Note: C is a higher magnification of B.
Structure Level Pattern Image Note
TS25: vibrissa follicle Strong Regionally restricted 5B , 5C Expression is in one part of the inner root sheath, absent in outer root sheath or in follicle cortical cells.

Specimen 6A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: intestine epithelium Absent 6A
TS21: intestine mesenchyme Absent 6A

Specimen 6B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: intestine epithelium Present Non-Uniform 6B
TS23: intestine mesenchyme Absent 6B

Specimen 6C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: intestine epithelium Present Non-Uniform 6C
TS25: intestine mesenchyme Absent 6C

Specimen 7A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pancreas Present Regionally restricted 7A Expression is in some acini.

Specimen 7B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: pancreas Strong 7B Expression is in almost all the acinar cells.

Specimen 8A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Absent 8A
TS21: metanephros Absent 8A
TS21: renal vasculature Absent 8A

Specimen 8B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cortical renal tubule Strong Regionally restricted 8B Expression is in the columnar epithelium of the convoluted tubules.
TS23: mesenchyme of metanephros Absent 8B
TS23: renal vasculature Absent 8B

Specimen 8C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical renal tubule Strong Regionally restricted 8C Expression is in the columnar epithelium of the convoluted tubules.
TS25: adrenal cortex Strong 8C
TS25: adrenal medulla Trace 8C The medulla is mostly negative for expression.
TS25: mesenchyme of metanephros Absent
TS25: renal vasculature Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory