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Gene Expression Data
Assay Details
Assay
Reference: J:49906 Kenny DA, et al., Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11257-62
Assay type: RNA in situ
MGI Accession ID: MGI:5609421
Gene symbol: Lmo4
Gene name: LIM domain only 4
Probe: LMO4pBSIIKS
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 9.0 (more )
Note: 16 somites.
Structure Level Pattern Image Note
TS14: migrating neural crest Present Regionally restricted 4A Expression is in migratory cranial crest.
TS14: paraxial mesenchyme Present Regionally restricted 4A Expression is dorsal in the caudal mesoderm.
TS14: somite Present Regionally restricted 4A Expression is rostral.
TS14: 1st branchial arch mandibular component mesenchyme Strong Regionally restricted 4A Expression is in ventral and dorsal mandibular mesenchyme.
Specimen 4Aa: embryonic day 9.0 (more )
Note: 16 somites.
Structure Level Pattern Image Note
TS14: paraxial mesenchyme Present Regionally restricted 4Aa Expression is dorsal in the caudal mesoderm.
Specimen 4Ab: embryonic day 9.0 (more )
Note: 16 somites.
Structure Level Pattern Image Note
TS14: somite Present Regionally restricted 4Ab Expression is rostral.
Specimen 4Ac: embryonic day 9.0 (more )
Note: 16 somites.
Structure Level Pattern Image Note
TS14: somite Present Regionally restricted 4Ac Expression is rostral.
TS14: dermomyotome Present 4Ac
Specimen 4Ad: embryonic day 9.0 (more )
Note: 16 somites.
Structure Level Pattern Image Note
TS14: 1st branchial arch mandibular component mesenchyme Present Regionally restricted 4Ad Expression is in ventral and dorsal mandibular mesenchyme.
TS14: migrating neural crest Present 4Ad
Specimen 4B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: somite Present Regionally restricted 4B Expression is in rostral somite halves of the first newly formed somites. At anterior levels expression is restricted to cells adjacent to the neural tube.
TS16: paraxial mesenchyme Present 4B
TS16: 1st branchial arch mandibular component mesenchyme Present Regionally restricted 4B Expression is restricted ventrally to the transitory mesenchyme that ultimately joins the left and right components of mandibular arch.
Specimen 4D: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: paraxial mesenchyme Present Regionally restricted 4D At anterior levels expression is restricted to cells adjacent to the neural tube.
TS16: somite Present Regionally restricted 4D At anterior levels expression is restricted to cells adjacent to the neural tube.
Specimen 4E: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: paraxial mesenchyme Present Regionally restricted 4E At anterior levels expression is restricted to cells adjacent to the neural tube.
TS16: somite Present Regionally restricted 4E At anterior levels expression is restricted to cells adjacent to the neural tube.
Specimen 4F: embryonic day 10.0; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS16: paraxial mesenchyme Present Regionally restricted 4F Expression is dorsal and is the same as in wild-type embryos.
TS16: branchial arch mesenchyme derived from neural crest Present Regionally restricted 4F Expression is in migratory cranial crest and is the same as in wild-type embryos.
TS16: somite Present Regionally restricted 4F The expression domain persists laterally in this mutant.
Specimen 4G: embryonic day 10.0; Mesp2tm1Ysa/Mesp2tm1Ysa (more )
Structure Level Pattern Image Note
TS16: tail unsegmented mesenchyme Present 4G
TS16: somite Absent 4G
Specimen 5C: embryonic day 11.5 (more )
Note: D,F are higher magnifications of C.
Structure Level Pattern Image Note
TS19: limb mesenchyme Present Regionally restricted 5D , 5F , 5C Expression is in the dorsal mesenchyme extending along the proximal-distal axis of the limb bud. Absent in the mesenchyme subjacent to the overlying ectoderm.
Specimen 5G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mandibular process mesenchyme Present Regionally restricted 5G Expression is restricted ventrally to the transitory mesenchyme that ultimately joins the left and right components of mandibular arch.
TS19: maxillary process mesenchyme Present 5G
TS19: nasal process ectoderm Present 5G
TS19: pharynx epithelium Present 5G
Specimen 5J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future pituitary Present Regionally restricted 5J Expression is anterior.
Specimen 5K: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis Present 5K
Specimen 5L: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 5L Expression is anterior.
TS19: semicircular canal Present 5L
Specimen 6B: embryonic day 11.5 (more )
Note: F is a higher magnification of B.
Structure Level Pattern Image Note
TS19: neural tube basal columns Present Regionally restricted 6B , 6F Expression is in apical paraventricular cells.
Specimen 6I: embryonic day 11.5 (more )
Note: K is a higher magnification of I.
Structure Level Pattern Image Note
TS19: spinal nerve Present Single cells 6K , 6I Expression is in cells tightly associated with spinal nerves.
TS19: dorsal root ganglion Absent 6I
Specimen not shown Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: thymus Present Widespread
Specimen not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cranial nerve Present Regionally restricted Expression is in early motor neurons of the ocularmotor nerve. Also in glial cells associated with cranial nerves.
TS19: hindbrain Present Regionally restricted Expression is in motor neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory