Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rab11atm1.1Ngao
Name:	RAB11A, member RAS oncogene family; targeted mutation 1.1, Nan Gao
MGI ID:	MGI:5608786
Synonyms:	Rab11afl
Gene:	Rab11a  Location: Chr9:64622582-64645038 bp, - strand  Genetic Position: Chr9, 34.87 cM, cytoband C
Alliance:	Rab11atm1.1Ngao page

Germline Transmission:	Earliest citation of germline transmission: J:215917
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted at 242 bp downstream of the second exon and a and a FRT-flanked PGK-neo cassette followed by a second loxP site was introduced at 210 bp downstream of the fourth exon. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:215917, J:222158)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rab11a Mutation:	13 strains or lines available

Original:	J:215917 Yu S, et al., TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J. 2014 Sep 1;33(17):1882-95
All:	8 reference(s)