Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nrxn1tm5Sud
Name:	neurexin I; targeted mutation 5, Thomas C Sudhof
MGI ID:	MGI:5605040
Synonyms:	Nrxn1flox
Gene:	Nrxn1  Location: Chr17:90341059-91400499 bp, - strand  Genetic Position: Chr17, 59.73 cM
Alliance:	Nrxn1tm5Sud page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 21, and a frt-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 21. Also, splice site 4, upstream of exon 21, was mutated to a canonical splice acceptor sequence. (J:101977)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nrxn1 Mutation:	95 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)