Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cyp26b1tm1Dcp
Name:	cytochrome P450, family 26, subfamily b, polypeptide 1; targeted mutation 1, David C Page
MGI ID:	MGI:5604888
Gene:	Cyp26b1  Location: Chr6:84548396-84570890 bp, - strand  Genetic Position: Chr6, 36.45 cM
Alliance:	Cyp26b1tm1Dcp page

Germline Transmission:	Earliest citation of germline transmission: J:215225
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 4-6 and the coding region of exon 7 were replaced by a loxP-flanked PGK-neomycin cassette via homologous recombination. (J:215225)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cyp26b1 Mutation:	35 strains or lines available

Original:	J:215225 Koubova J, et al., Retinoic acid activates two pathways required for meiosis in mice. PLoS Genet. 2014 Aug;10(8):e1004541
All:	1 reference(s)