Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(ICAM1)4Grom
Name:	transgene insertion 4, Matthias Gromeier
MGI ID:	MGI:5604232
Synonyms:	HsICAM-1 tg
Transgene:	Tg(ICAM1)4Grom  Location: unknown
Alliance:	Tg(ICAM1)4Grom page

Strain of Origin:

FVB/NHsd

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(ICAM1)4Grom expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human ICAM1 (3383) Icam1  (MGI:96392)   Mutation details: A ~39 kbp segment was isolated from BAC CTD-2369P2 containing the entire human intercellular adhesion molecule 1 gene (ICAM1), including ~18.9 kbp upstream and ~4.6 kbp downstream. Five founder lines were generated and founder line 4 was determined to have hICAM-1 expression intensity and tissue distribution similar to human. (J:92607)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:92607 Dufresne AT, et al., A nonpolio enterovirus with respiratory tropism causes poliomyelitis in intercellular adhesion molecule 1 transgenic mice. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13636-41
All:	2 reference(s)