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Gene Expression Data
Assay Details
Assay
Reference: J:211539 Chen Y, et al., Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5603145
Gene symbol: Snai2
Gene name: snail family zinc finger 2
Reporter: lacZ
Direct Detection
Results
Specimen S7A/D: embryonic day 16.5; Snai1tm2Grid/Snai1tm2Grid, Snai2tm1Grid/Snai2+ (more )
Note: the Snai1 allele is floxed (but uncut)
Structure Level Pattern Image Note
TS24: femur Present Regionally restricted S7A , S7D Expression is in proliferating chondrocytes in the growth plate.
Specimen S7B/E: embryonic day 16.5; Snai1tm2Grid/Snai1tm2Grid, Snai2tm1Grid/Snai2tm1Grid (more )
Note: the Snai1 allele is floxed (but uncut)
Structure Level Pattern Image Note
TS24: femur Present Regionally restricted S7B , S7E As in heterozygotes, expression is in proliferating chondrocytes in the growth plate. However, expression levels in the homozygote are increased relative to those seen in the heterozygote.
Specimen S7C/F: embryonic day 16.5; Snai1tm1Grid/Snai1tm1Grid, Snai2tm1Grid/Snai2tm1Grid, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: femur Present Regionally restricted S7C , S7F Expression is in proliferating chondrocytes in the growth plate. However, in the double mutant expression is also seen in hypertrophic chondrocytes and expression levels are increased relative to those seen in Snai2 heterozygotes and homozygotes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory