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Tg(MECP2/EGFP)1Hzo
Transgene Detail
Summary
Symbol: Tg(MECP2/EGFP)1Hzo
Name: transgene insertion 1, Huda Y Zoghbi
MGI ID: MGI:5588443
Transgene: Tg(MECP2/EGFP)1Hzo  Location: unknown  
Alliance: Tg(MECP2/EGFP)1Hzo page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(MECP2/EGFP)1Hzo expresses 1 gene
 
Mutation detailsThe transgenic construct contains a human PAC (PAC671D9) with the entire human MECP2 locus and its essential regulatory elements and a C-terminal GFP tag. (J:214143)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:214143 Heckman LD, et al., Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice. Elife. 2014;3
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory