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Gng8tm1(tTA)Rtir
Targeted Allele Detail
Summary
Symbol: Gng8tm1(tTA)Rtir
Name: guanine nucleotide binding protein (G protein), gamma 8; targeted mutation 1, Roberto Tirindelli
MGI ID: MGI:5584308
Synonyms: Ggamma8-
Gene: Gng8  Location: Chr7:16625711-16629361 bp, + strand  Genetic Position: Chr7, 9.15 cM
Alliance: Gng8tm1(tTA)Rtir page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:212780
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Transactivator)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding sequence was replaced with a tetracycline transactivator (tTA) and neomycin resistance cassette. (J:212780)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gng8 Mutation:  10 strains or lines available
References
Original:  J:212780 Montani G, et al., Aggressive behaviour and physiological responses to pheromones are strongly impaired in mice deficient for the olfactory G-protein -subunit G8. J Physiol. 2013 Aug 15;591(Pt 16):3949-62
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory