Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(tetO-Fgfr2b/Igh)1.3Jaw
Name:	transgene insertion 1.3, Jeffrey A Whitsett
MGI ID:	MGI:5582625
Synonyms:	(tetO)7-CMV-FGFR-HFc, Tet-sFgfr2b
Transgene:	Tg(tetO-Fgfr2b/Igh)1.3Jaw  Location: unknown
Alliance:	Tg(tetO-Fgfr2b/Igh)1.3Jaw page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(tetO-Fgfr2b/Igh)1.3Jaw expresses 2 genes Transgene expresses: Organism Expressed Gene Note mouse Fgfr2 (MGI:95523) mouse Igh (MGI:96442)   Mutation details: A transgenic vector containing the soluble chimeric dominant-negative FGFR-HFc construct, which consists of the extracellular domain of the mouse Fgfr2b gene and the heavy chain hinge and Fc domain of the mouse immunoglobulin, under control of a tetracycline operator (tetO)7/minimal cytomegalovirus (CMV) promoter, was utilized in the construction of this transgenic strain. Founder lines 1.3 and 5.9 were generated, it is not known how they compare to each other. (J:101977, J:133366)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	21 reference(s)