Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(HSV-Hoxd4)70Cka
Name:	transgene insertion 70, Claudia Kappen
MGI ID:	MGI:5578562
Synonyms:	IE-Hoxd-4
Transgene:	Tg(HSV-Hoxd4)70Cka  Location: unknown
Alliance:	Tg(HSV-Hoxd4)70Cka page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(HSV-Hoxd4)70Cka expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Hoxd4 (MGI:96208)   Mutation details: The transresponder transgene contains mouse Hoxd4 cDNA under the control of the VP-16 responsive HSV immediate early (IE) promoter. A c-myc (Myc) epitope tag and SV40 poly-A sequence is inserted at the 3' end of the coding region. Transgene expression is activated when a transresponder mouse is combined with a transactivator mouse carrying the viral coactivator VP16 under the control of a promoter of interest. Expression is limited to regions in the mouse embryo where VP16 is present. (J:48458)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:48458 Rundle CH, et al., Transactivation of Hox gene expression in a VP16-dependent binary transgenic mouse system. Biochim Biophys Acta. 1998 Jun 16;1398(2):164-78
All:	1 reference(s)