Hprt1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:208718 Selmi-Ruby S, et al., The targeted inactivation of TRbeta gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production. Endocrinology. 2014 Feb;155(2):635-46
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5576939
Gene symbol:	Hprt1
Gene name:	hypoxanthine phosphoribosyltransferase 1

Reporter:	Cre
Antibody:	anti-cre
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

Specimen 1D b: postnatal adult; Hprt1^{tm1(TG-cre)1Sasr}/Y (more

)
Note: Basal conditions.

Structure	Level	Pattern	Image	Note
TS28: thyroid gland	Present	Uniform	1D b	Staining is nuclear.

Specimen 1D d: postnatal adult; Hprt1^{tm1(TG-cre)1Sasr}/Y (more

)
Note: TSH stimulated conditions.

Structure	Level	Pattern	Image	Note
TS28: thyroid gland	Present	Uniform	1D d	Staining is nuclear.

Specimen 1D e: postnatal adult; Hprt1^{tm1(TG-cre)1Sasr}/Hprt1⁺ (more

)
Note: TSH stimulated conditions.

Structure	Level	Pattern	Image	Note
TS28: thyroid gland	Present	Non-Uniform	1D e	Staining is nuclear. Due to random X-chromosome inactivation, staining is seen in patches.

Specimen 1D f: postnatal adult; Hprt1^{tm1(TG-cre)1Sasr}/Hprt1^{tm1(TG-cre)1Sasr} (more

)
Note: TSH stimulated conditions.

Structure	Level	Pattern	Image	Note
TS28: thyroid gland	Present	Uniform	1D f	Staining is nuclear.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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