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Gene Expression Data
Assay Details
Assay
Reference: J:156934 Santisteban P, et al., Dynamic expression of groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation. Dev Dyn. 2010 Jan 27;239(3):980-986
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5572006
Gene symbol: Tle3
Gene name: transducin-like enhancer of split 3
Antibody: anti-Grg3
Detection system: Secondary antibody
Results
Specimen 3B: embryonic day 8.5 (more )
Note: 6-7 somite pair stage
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present Regionally restricted 3B Nuclear staining in ventral foregut endoderm.
Specimen 3H/I: embryonic day 8.0 (more )
Note: Double labeled: red - Tle3; green - Foxa2 (assay MGI:5572018). 3-4 somite pair stage
Structure Level Pattern Image Note
TS12: foregut diverticulum endoderm Present Regionally restricted 3I , 3H Nuclear staining in ventral foregut endoderm.
Specimen 3L/M: embryonic day 8.5 (more )
Note: Double labeled: red - Tle3; green - Foxa2 (assay MGI:5572018). 8-9 somite pair stage
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present Regionally restricted 3L , 3M Nuclear staining in ventral foregut endoderm.
Specimen 4C/D: embryonic day 9.0 (more )
Note: Double labeled: red - Tle3; green - Foxa2 (assay MGI:5572018). 13 somite pair stage
Structure Level Pattern Image Note
TS14: hepatic primordium Absent 4C , 4D
TS14: neural tube floor plate Present 4C , 4D
Specimen 4G/H: embryonic day 9.5 (more )
Note: Double labeled: red - Tle3; green - Foxa2 (assay MGI:5572018). 20 somite pair stage
Structure Level Pattern Image Note
TS15: hepatic primordium Absent 4G , 4H
TS15: neural tube floor plate Absent 4G , 4H
TS15: foregut-midgut junction mesenchyme Present Regionally restricted 4G , 4H Expressed in the stromal cells that surround the liver bud.
TS15: midgut epithelium Present 4H , 4G
Specimen 4K/L: embryonic day 9.5 (more )
Note: Double labeled: red - Tle3; green - Foxa2 (assay MGI:5572018). 22-23 somite pair stage
Structure Level Pattern Image Note
TS15: hepatic primordium Absent 4K , 4L
Specimen 4N: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Absent 4N
TS20: liver and biliary system Present Regionally restricted 4N Expressed in the mesothelium (liver capsule).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory