Smoc1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:153731 Pazin DE, et al., Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation. Dev Dyn. 2009 Nov;238(11):2877-90
Assay type:	RNA in situ
MGI Accession ID:	MGI:5569089
Gene symbol:	Smoc1
Gene name:	SPARC related modular calcium binding 1

Probe:	Smoc1 cDNA
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

1A E10.5 XX ©

Specimen 1A E10.5 XX: embryonic day 10.5 (more

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Structure	Level	Pattern	Image	Note
TS17: gonad primordium	Absent		1A E10.5 XX
TS17: mesonephros	Absent		1A E10.5 XX

1A E10.5 XY ©

Specimen 1A E10.5 XY: embryonic day 10.5 (more

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Structure	Level	Pattern	Image	Note
TS17: gonad primordium	Absent		1A E10.5 XY
TS17: mesonephros	Absent		1A E10.5 XY

1A E11.5 XX ©

Specimen 1A E11.5 XX: embryonic day 11.5 (more

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Structure	Level	Pattern	Image	Note
TS19: gonad	Present		1A E11.5 XX
TS19: mesonephros	Absent		1A E11.5 XX

1A E11.5 XY ©

Specimen 1A E11.5 XY: embryonic day 11.5 (more

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Structure	Level	Pattern	Image	Note
TS19: gonad	Present		1A E11.5 XY
TS19: mesonephros	Absent		1A E11.5 XY

1A E12.5 XX ©

Specimen 1A E12.5 XX: embryonic day 12.5 (more

)

Structure	Level	Image
TS20: ovary	Present	1A E12.5 XX
TS20: coelomic epithelium of female mesonephros	Absent	1A E12.5 XX
TS20: mesonephros of female	Absent	1A E12.5 XX
TS20: surface epithelium of ovary	Absent	1A E12.5 XX

1A E12.5 XY ©

Specimen 1A E12.5 XY: embryonic day 12.5 (more

)

Structure	Level	Image
TS20: primary sex cord	Present	1A E12.5 XY
TS20: coelomic epithelium of male mesonephros	Absent	1A E12.5 XY
TS20: coelomic epithelium of testis	Absent	1A E12.5 XY
TS20: mesonephros of male	Absent	1A E12.5 XY

1A E13.5 XX ©

Specimen 1A E13.5 XX: embryonic day 13.5 (more

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Structure	Level	Pattern	Image	Note
TS21: ovary	Present	Non-Uniform	1A E13.5 XX	Strong in the posterior half, downregulated in the anterior half.
TS21: coelomic epithelium of female mesonephros	Absent		1A E13.5 XX
TS21: mesonephros of female	Absent		1A E13.5 XX
TS21: surface epithelium of ovary	Absent		1A E13.5 XX

1A E13.5 XY ©

Specimen 1A E13.5 XY: embryonic day 13.5 (more

)

Structure	Level	Image
TS21: primary sex cord	Present	1A E13.5 XY
TS21: coelomic epithelium of male mesonephros	Absent	1A E13.5 XY
TS21: coelomic epithelium of testis	Absent	1A E13.5 XY
TS21: mesonephros of male	Absent	1A E13.5 XY

1A E14.5 XX ©

Specimen 1A E14.5 XX: embryonic day 14.5 (more

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Structure	Level	Pattern	Image	Note
TS22: ovary	Present	Non-Uniform	1A E14.5 XX	Strong at the posterior-most end, downregulated in the rest of the ovary.
TS22: coelomic epithelium of female mesonephros	Absent		1A E14.5 XX
TS22: mesonephros of female	Absent		1A E14.5 XX
TS22: surface epithelium of ovary	Absent		1A E14.5 XX

1A E14.5 XY ©

Specimen 1A E14.5 XY: embryonic day 14.5 (more

)

Structure	Level	Image
TS22: primary sex cord	Present	1A E14.5 XY
TS22: coelomic epithelium of male mesonephros	Absent	1A E14.5 XY
TS22: coelomic epithelium of testis	Absent	1A E14.5 XY
TS22: mesonephros of male	Absent	1A E14.5 XY

1A E15.5 XX ©

Specimen 1A E15.5 XX: embryonic day 15.5 (more

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Structure	Level	Image
TS23: ovary	Weak	1A E15.5 XX
TS23: coelomic epithelium of female mesonephros	Absent	1A E15.5 XX
TS23: mesonephros of female	Absent	1A E15.5 XX
TS23: surface epithelium of ovary	Absent	1A E15.5 XX

1A E15.5 XY ©

Specimen 1A E15.5 XY: embryonic day 15.5 (more

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Structure	Level	Image
TS23: testis	Weak	1A E15.5 XY
TS23: coelomic epithelium of male mesonephros	Absent	1A E15.5 XY
TS23: coelomic epithelium of testis	Absent	1A E15.5 XY
TS23: mesonephros of male	Absent	1A E15.5 XY

1C XX ©

Specimen 1C XX: embryonic day 13.5; Kit^W-v/Kit^W-v (more

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Structure	Level	Pattern	Image	Note
TS21: ovary	Present		1C XX	Expression in this mutant is the same as in wild-type.

1C XY ©

Specimen 1C XY: embryonic day 13.5; Kit^W-v/Kit^W-v (more

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Structure	Cell Type	Level	Pattern	Image	Note
TS21: testis		Present		1C XY	Expression in this mutant is the same as in wild-type.
TS21: Sertoli cell	Sertoli cell	Present		1C XY

3_XX 10-11ts ©

Specimen 3 XX 10-11ts: embryonic day 10.75 (more

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Structure	Level	Pattern	Image	Note
TS18: gonad primordium	Present	Regionally restricted	3_XX 10-11ts	Expression is in the center.

3_XY 10-11ts ©

Specimen 3 XY 10-11ts: embryonic day 10.75 (more

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Structure	Level	Pattern	Image	Note
TS18: gonad primordium	Present	Regionally restricted	3_XY 10-11ts	Expression is in the center.

3_XX 11-13ts ©

Specimen 3 XX 11-13ts: embryonic day 11.0 (more

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Structure	Level	Pattern	Image	Note
TS18: gonad primordium	Present	Regionally restricted	3_XX 11-13ts	Expression is in the center and spreads toward both the anterior and posterior poles.

3_XY 11-13ts ©

Specimen 3 XY 11-13ts: embryonic day 11.0 (more

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Structure	Level	Pattern	Image	Note
TS18: gonad primordium	Present	Regionally restricted	3_XY 11-13ts	Expression is in the center and spreads toward both the anterior and posterior poles.

3_XX 15ts ©

Specimen 3 15ts XX: embryonic day 11.25 (more

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Structure	Level	Pattern	Image	Note
TS18: gonad primordium	Present	Regionally restricted	3_XX 15ts	Expression is in the center and spreads toward both the anterior and posterior poles.

3_XY 15ts ©

Specimen 3 15ts XY: embryonic day 11.25 (more

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Structure	Level	Pattern	Image	Note
TS18: gonad primordium	Present	Regionally restricted	3_XY 15ts	Expression is in the center and spreads toward both the anterior and posterior poles.

3_XX 16-17ts ©

Specimen 3 16-17ts XX: embryonic day 11.4 (more

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Structure	Level	Pattern	Image	Note
TS19: gonad	Present	Regionally restricted	3_XX 16-17ts	Expression is in the center and spreads toward both the anterior and posterior poles.

3_XY 16-17ts ©

Specimen 3 16-17ts XY: embryonic day 11.4 (more

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Structure	Level	Pattern	Image	Note
TS19: gonad	Present	Regionally restricted	3_XY 16-17ts	Expression is in the center and spreads toward both the anterior and posterior poles.

3_XX 19ts ©

Specimen 3 19ts XX: embryonic day 11.6 (more

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Structure	Level	Pattern	Image	Note
TS19: gonad	Present		3_XX 19ts	Expression is along the entire length of the gonad.

3_XY 19ts ©

Specimen 3 19ts XY: embryonic day 11.6 (more

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Structure	Level	Pattern	Image	Note
TS19: gonad	Present		3_XY 19ts	Expression is along the entire length of the gonad.

5_XX Sf1 +/+ ©

Specimen 5 Sf1+/+ XX: embryonic day 11.5 (more

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Structure	Level	Pattern	Image	Note
TS19: gonad	Present		5_XX Sf1 +/+
TS19: mesonephros	Absent		5_XX Sf1 +/+

5_XY Sf1 +/+ ©

Specimen 5 Sf1+/+ XY: embryonic day 11.5 (more

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Structure	Level	Pattern	Image	Note
TS19: gonad	Present		5_XY Sf1 +/+
TS19: mesonephros	Absent		5_XY Sf1 +/+

5_XX Sf1 +/- ©

Specimen 5 Sf1+/- XX: embryonic day 11.5; Nr5a1^tm1Klp/Nr5a1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: gonad	Weak		5_XX Sf1 +/-
TS19: mesonephros	Absent		5_XX Sf1 +/-

5_XY Sf1 +/- ©

Specimen 5 Sf1+/- XY: embryonic day 11.5; Nr5a1^tm1Klp/Nr5a1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: gonad	Weak		5_XY Sf1 +/-
TS19: mesonephros	Absent		5_XY Sf1 +/-

5_XX Sf1 -/- ©

Specimen 5 Sf1-/- XX: embryonic day 11.5; Nr5a1^tm1Klp/Nr5a1^tm1Klp (more

)

Structure	Level	Pattern	Image	Note
TS19: gonad	Absent		5_XX Sf1 -/-
TS19: mesonephros	Absent		5_XX Sf1 -/-

5_XY Sf1 -/- ©

Specimen 5 Sf1-/- XY: embryonic day 11.5; Nr5a1^tm1Klp/Nr5a1^tm1Klp (more

)

Structure	Level	Pattern	Image	Note
TS19: gonad	Absent		5_XY Sf1 -/-
TS19: mesonephros	Absent		5_XY Sf1 -/-

9A Smoc1 ©

Specimen 9A: embryonic day 13.5 (more

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Structure	Level	Pattern	Image	Note
TS21: adrenal gland	Present	Regionally restricted	9A Smoc1	Expression is in the medulla.
TS21: metanephros	Present	Regionally restricted	9A Smoc1	Expression is in the ureter, absent in kidney.
TS21: ureter	Present		9A Smoc1

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