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Khdrbs2tm1.1Schei
Targeted Allele Detail
Summary
Symbol: Khdrbs2tm1.1Schei
Name: KH domain containing, RNA binding, signal transduction associated 2; targeted mutation 1.1, Peter Scheiffele
MGI ID: MGI:5568964
Synonyms: Slm1KO
Gene: Khdrbs2  Location: Chr1:32211795-32697649 bp, + strand  Genetic Position: Chr1, 11.86 cM, cytoband B
Alliance: Khdrbs2tm1.1Schei page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:208331
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon2 and an FRT-flanked neo cassette flanked by two loxP sites were removed following cre-mediated recombination. Western blot analysis showed an absent of protein expression. (J:208331)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Khdrbs2 Mutation:  25 strains or lines available
References
Original:  J:208331 Iijima T, et al., Neuronal cell type-specific alternative splicing is regulated by the KH domain protein SLM1. J Cell Biol. 2014 Feb 3;204(3):331-42
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory