Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Reltm1Ukl
Name:	reticuloendotheliosis oncogene; targeted mutation 1, Ulf Klein
MGI ID:	MGI:5568752
Gene:	Rel  Location: Chr11:23686847-23720969 bp, - strand  Genetic Position: Chr11, 14.36 cM
Alliance:	Reltm1Ukl page

Germline Transmission:	Earliest citation of germline transmission: J:228566
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: Sequence encoding a promoterless eGFP minigene, a loxP site and the PGKneo cassette was inserted upstream of exon 1 of the targeted gene, and another loxP site followed by the PGK promoter was inserted downstream of exon 1. The entire targeted region was flanked by FRT sites. (J:228566)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rel Mutation:	44 strains or lines available

Original:	J:228566 Heise N, et al., Germinal center B cell maintenance and differentiation are controlled by distinct NF-kappaB transcription factor subunits. J Exp Med. 2014 Sep 22;211(10):2103-18
All:	11 reference(s)