Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grptm1Jfb
Name:	gastrin releasing peptide; targeted mutation 1, James F Battey
MGI ID:	MGI:5565455
Gene:	Grp  Location: Chr18:66005891-66019667 bp, + strand  Genetic Position: Chr18, 38.98 cM
Alliance:	Grptm1Jfb page

Germline Transmission:	Earliest citation of germline transmission: J:205122
Parent Cell Line:	GSI-1 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replaced with a neo cassette. Immunostaining analysis confirmed the absence of expression in dorsal root ganglion and spinal cord neurons. (J:205122)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grp Mutation:	30 strains or lines available

Original:	J:205122 Zhao ZQ, et al., Chronic itch development in sensory neurons requires BRAF signaling pathways. J Clin Invest. 2013 Nov 1;123(11):4769-80
All:	6 reference(s)