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Del(16Tiam1-Il10rb)9Yey
Targeted Allele Detail
Summary
Symbol: Del(16Tiam1-Il10rb)9Yey
Name: deletion, Chr 16, Y Eugene Yu 9
MGI ID: MGI:5561089
Synonyms: Del(16Tiam1-Il10rb)3Yey, Del9Yey, Df(16)3Yey, Df(16Tiam1-Il10rb)Yey, Ms4Yey
Gene: Del(16Tiam1-Il10rb)9Yey  Location: unknown  Genetic Position: Chr16, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:208104
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion, Intragenic deletion
  Del(16Tiam1-Il10rb)9Yey involves 43 genes/genome features (Gm35834, Gm35774, Gm22933 ...) View all
 
Mutation detailsThis deletion was generated by recombination between two MICER clone insertions (MHPn374h24 and MHPP321i13). The 2.1 Mb deletion spans Tiam1 to Il10rb. The tyrosinase and Agouti transgenes from the MICER clones remain. (J:208104)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Del(16Tiam1-Il10rb)9Yey Mutation:  1 strain or line available
References
Original:  J:208104 Liu C, et al., Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice. Hum Genet. 2014 Jun;133(6):743-53
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory