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Gt(ROSA)26Sortm1(CAG-EGFP/Rpl10)Dolsn
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(CAG-EGFP/Rpl10)Dolsn
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, David P Olson
MGI ID: MGI:5559562
Synonyms: R26-loxSTOPlox-L10-GFP, R26-LSL-L10GFP, Rosa26eGFP-L10a
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(CAG-EGFP/Rpl10)Dolsn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:207472
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsA transgene was generated where a floxed transcription STOP cassette followed by an EGFP/Rpl10 fusion reporter gene under control of the CAG promoter (CVM enhancer/chicken ACTB promoter). This construct was targeted to the Gt(ROSA)26Sor locus in ES cells. (J:207472)
Expression
In Mice Carrying this Mutation: 2 assay results
1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:207472 Krashes MJ, et al., An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger. Nature. 2014 Mar 13;507(7491):238-42
All:  55 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory