Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wapltm1.2Jmpt
Name:	WAPL cohesin release factor; targeted mutation 1.2, Jan-Michael Peters
MGI ID:	MGI:5551807
Synonyms:	Wapldelta
Gene:	Wapl  Location: Chr14:34395885-34469940 bp, + strand  Genetic Position: Chr14, 20.84 cM
Alliance:	Wapltm1.2Jmpt page

Germline Transmission:	Earliest citation of germline transmission: J:205429
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the resistance cassette. Cre-mediated recombination removed exons 3 and 4. (J:205429)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wapl Mutation:	168 strains or lines available

Original:	J:205429 Tedeschi A, et al., Wapl is an essential regulator of chromatin structure and chromosome segregation. Nature. 2013 Sep 26;501(7468):564-8
All:	1 reference(s)