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Gene Expression Data
Assay Details
Assay
Reference: J:108819 Miyoshi T, et al., Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants. Dev Dyn. 2006 Apr 5;235(7):1941-1952
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5550530
Gene symbol: Zeb1
Gene name: zinc finger E-box binding homeobox 1
Reporter: lacZ
Direct Detection
Results
Specimen 2Ab: embryonic day 7.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS11: embryo Present 2Ab
TS11: primitive streak Present 2Ab
TS11: future spinal cord neural plate Present Regionally restricted 2Ab Expressed in the neural groove.
Specimen 2Ad: embryonic day 7.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: embryo ectoderm Present Widespread 2Ad Expressed widely in the primitive ectoderm.
Specimen 2Bb: embryonic day 8.0; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: neural fold Present 2Bb
TS12: node Present 2Bb
TS12: embryo Present Widespread 2Bb
Specimen 2Bd: embryonic day 8.0; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: neural fold Strong 2Bd
TS12: node Strong 2Bd
TS12: notochordal plate Strong 2Bd Prechordal plate.
Specimen 2Bf: embryonic day 8.0; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: head mesenchyme Strong 2Bf
TS12: future spinal cord neural plate Present 2Bf
Specimen 2Bh: embryonic day 8.0; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS12: primitive streak Present 2Bh
Specimen 2Cb left: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Weak Regionally restricted 2Cb left Very weak expression, except for the most anterior region and rhombomeres 3 and 5.
TS13: anterior pro-rhombomere neural fold Present Regionally restricted 2Cb left Expressed in the most anterior region.
TS13: rhombomere 3 Present 2Cb left
TS13: rhombomere 5 Present 2Cb left
Specimen 2Cb right: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 2Cb right Very weak expression, except for the most anterior region and rhombomeres 3 and 5.
TS13: node Present 2Cb right
TS13: rhombomere 3 Present 2Cb right
TS13: rhombomere 5 Present 2Cb right
TS13: anterior pro-rhombomere neural fold Present Regionally restricted 2Cb right Expressed in the most anterior region.
Specimen 2Cd: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: future prosencephalon Present 2Cd
TS13: future midbrain Ambiguous 2Cd Low level or no expression.
Specimen 2Cf: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: neural tube Ambiguous 2Cf Low level or no expression.
TS13: somite Ambiguous 2Cf Low level or no expression.
TS13: embryo endoderm Present 2Cf
TS13: node Present 2Cf
TS13: notochord Present 2Cf
Specimen 2Ch: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 9 somite
Structure Level Pattern Image Note
TS13: node Present 2Ch
TS13: future spinal cord neural plate Ambiguous 2Ch Low level or no expression.
Specimen 3Ab: embryonic day 9.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 3Ab
TS15: forelimb bud Present 3Ab
TS15: myotome Present 3Ab
TS15: trigeminal preganglion Present 3Ab
Specimen 3Bb: embryonic day 10.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS17: acoustic ganglion Present 3Bb
TS17: facial ganglion Present 3Bb
TS17: glossopharyngeal ganglion Present 3Bb
TS17: limb Present 3Bb
TS17: myotome Present 3Bb
TS17: trigeminal ganglion Present 3Bb
TS17: vagus ganglion Present 3Bb
Specimen 3Bd: embryonic day 10.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS17: myotome Present 3Bd
TS17: notochord Present 3Bd
Specimen 3Cb: embryonic day 11.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS19: embryo Present 3Cb
Specimen 3Cd: embryonic day 11.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS19: maxilla primordium Present Regionally restricted 3Cd Expressed in the medial part.
TS19: nasal pit Present 3Cd Expressed in the nasal pit.
TS19: nose Present Regionally restricted 3Cd Expressed in the vomeronasal organ.
Specimen 3Cf: embryonic day 11.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 3Cf Expressed in the choroid invagination and the subventricular zone of corpus striatum.
TS19: Rathke's pouch Present 3Cf
TS19: trigeminal ganglion Present 3Cf
Specimen 3Ch: embryonic day 11.5; Zeb1tm2Yhi/Zeb1+ (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 3Ch
TS19: myotome Present 3Ch
TS19: notochord Present 3Ch
TS19: neural tube lateral wall Present Regionally restricted 3Ch Expressed in the motoneurons in the ventral horn, and to a lesser extent in the interneurons in the medial part.
Specimen 4Aa: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 4 somite
Structure Level Pattern Image Note
TS13: neural fold Present 4Aa
TS13: paraxial mesenchyme Present 4Aa
Specimen 4Ab: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+, Zeb2tm1.2Yhi/Zeb2+ (more )
Note: 4 somite
Structure Level Pattern Image Note
TS13: neural fold Present 4Ab
TS13: paraxial mesenchyme Present 4Ab
Specimen 4Ac: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+, Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 4 somite
Structure Level Pattern Image Note
TS13: neural fold Present Regionally restricted 4Ac Increased expression in neural folds from the anterior margin to the level of the hindbrain rhombomeres (including r3).
TS13: paraxial mesenchyme Present Regionally restricted 4Ac Increased expression in the posterior domains.
Specimen 4Ba: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: neural fold Present 4Ba
Specimen 4Bb: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: rhombomere 3 neural fold Present 4Bb
Specimen 4Bc: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: rhombomere 4 neural fold Weak 4Bc
Specimen 4Bd: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+ (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: paraxial mesenchyme Weak 4Bd
Specimen 4Be: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+, Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: neural fold Present Regionally restricted 4Be Increased expression in neural folds from the anterior margin to the level of the hindbrain rhombomeres (including r3).
TS13: paraxial mesenchyme Present Regionally restricted 4Be Increased expression in the posterior domains.
Specimen 4Bf: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+, Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: rhombomere 3 neural fold Present 4Bf Increased expression compared with control.
Specimen 4Bg: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+, Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: rhombomere 4 neural fold Present 4Bg Increased expression compared with control.
Specimen 4Bh: embryonic day 8.5; Zeb1tm2Yhi/Zeb1+, Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Note: 7 somite
Structure Level Pattern Image Note
TS13: paraxial mesenchyme Present 4Bh 5 fold increase compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory