Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(ACTA1-MAP2K6)#Jmol
Name:	transgene insertion, Jeffery Molkentin
MGI ID:	MGI:5550391
Transgene:	Tg(ACTA1-MAP2K6)#Jmol  Location: unknown
Alliance:	Tg(ACTA1-MAP2K6)#Jmol page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(ACTA1-MAP2K6)#Jmol expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human MAP2K6 (5608) Map2k6  (MGI:1346870)   Mutation details: Expression of constitutively active human MAP2K6 (MKK6) with a polyA tail is driven by the human ACTA1 promoter in this transgene. (J:219250)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:219250 Wissing ER, et al., P38alpha MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism. Hum Mol Genet. 2014 Oct 15;23(20):5452-63
All:	1 reference(s)