Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Vxntm1b(KOMP)Wtsi
Name:	vexin; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID:	MGI:5548679
Gene:	Vxn  Location: Chr1:9671492-9697367 bp, + strand  Genetic Position: Chr1, 2.08 cM
Alliance:	Vxntm1b(KOMP)Wtsi page
IMPC:	Vxn gene page

Mutant Cell Line:	EPD0684_4_A05
Germline Transmission:	Earliest citation of germline transmission: J:204739
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: Cre-mediated excision of the parental 3110035E14Riktm1a(KOMP)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Vxn Mutation:	15 strains or lines available

Original:	J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:	2 reference(s)