Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Abca8btm1b(EUCOMM)Wtsi
Name:	ATP-binding cassette, sub-family A member 8b; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID:	MGI:5548477
Gene:	Abca8b  Location: Chr11:109823016-109886671 bp, - strand  Genetic Position: Chr11, 72.88 cM
Alliance:	Abca8btm1b(EUCOMM)Wtsi page
IMPC:	Abca8b gene page

Mutant Cell Line:	EPD0454_4_E08
Germline Transmission:	Earliest citation of germline transmission: J:204739
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	EUCOMM

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: Cre-mediated excision of the parental Abca8btm1a(EUCOMM)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

In Mice Carrying this Mutation:

24 assay results 1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Abca8b Mutation:	110 strains or lines available

Original:	J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:	2 reference(s)