Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Dnaaf4tm1.1Jjlo
Name:	dynein axonemal assembly factor 4; targeted mutation 1.1, Joseph J LoTurco
MGI ID:	MGI:5547587
Synonyms:	Dyx1c1flox2-4
Gene:	Dnaaf4  Location: Chr9:72866067-72880346 bp, + strand  Genetic Position: Chr9, 40.08 cM, cytoband D
Alliance:	Dnaaf4tm1.1Jjlo page

Germline Transmission:	Earliest citation of germline transmission: J:205312
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neomycin resistance cassette and left exons 2 through 4 floxed. (J:205312)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnaaf4 Mutation:	21 strains or lines available

Original:	J:205312 Tarkar A, et al., DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Sep;45(9):995-1003
All:	2 reference(s)