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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5543150
Gene symbol: Srd5a2
Gene name: steroid 5 alpha-reductase 2
Probe: CVprobeSrd5a2(0145)
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:14313: embryonic day 14.0 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS22: mesonephric mesenchyme of male Absent GUDMAP:14313
TS22: nephric duct of male, mesonephric portion Absent GUDMAP:14313
TS22: mesonephros of male Absent GUDMAP:14313
TS22: male reproductive system Absent GUDMAP:14313
TS22: reproductive system Absent GUDMAP:14313
TS22: muscle layer of pelvic urethra Absent GUDMAP:14313
TS22: epithelium of pelvic urethra Absent GUDMAP:14313
TS22: bladder Absent GUDMAP:14313
TS22: muscle layer of dorsal pelvic urethra Absent GUDMAP:14313
TS22: muscle layer of ventral pelvic urethra Absent GUDMAP:14313
TS22: mesenchymal layer of ventral pelvic urethra Present Regionally restricted GUDMAP:14313 Expression present along length of urethra only.
TS22: mesenchymal layer of dorsal pelvic urethra Present Regionally restricted GUDMAP:14313 Strong expression in group of cells located near urogenital sinus. Moderate expression extends along length of urethra only.
TS22: mesenchymal layer of pelvic urethra Present GUDMAP:14313
TS22: pelvic urethra Present GUDMAP:14313
TS22: urethra Present GUDMAP:14313
TS22: vasculature of bladder Absent GUDMAP:14313
TS22: adventitia of ventral bladder neck Absent GUDMAP:14313
TS22: adventitia of bladder trigone Absent GUDMAP:14313
TS22: serosa of bladder fundus Absent GUDMAP:14313
TS22: serosa of bladder Absent GUDMAP:14313
TS22: detrusor muscle of ventral bladder neck Absent GUDMAP:14313
TS22: detrusor muscle of bladder trigone Absent GUDMAP:14313
TS22: detrusor muscle of bladder fundus Absent GUDMAP:14313
TS22: detrusor muscle of bladder Absent GUDMAP:14313
TS22: lamina propria of ventral bladder neck Absent GUDMAP:14313
TS22: lamina propria of bladder trigone Absent GUDMAP:14313
TS22: lamina propria of bladder fundus Absent GUDMAP:14313
TS22: lamina propria of bladder Absent GUDMAP:14313
TS22: urothelium of ventral bladder neck Absent GUDMAP:14313
TS22: urothelium of bladder trigone Absent GUDMAP:14313
TS22: urothelium of bladder fundus Absent GUDMAP:14313
TS22: basal cell layer of bladder urothelium Absent GUDMAP:14313
TS22: superficial cell layer of bladder urothelium Absent GUDMAP:14313
TS22: urothelium of bladder Absent GUDMAP:14313
TS22: urinary system Present GUDMAP:14313
Specimen GUDMAP:14314: embryonic day 14.0 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS22: mesenchyme of rest of paramesonephric duct of female Absent GUDMAP:14314
TS22: epithelium of rest of paramesonephric duct of female Absent GUDMAP:14314
TS22: paramesonephric duct of female, rest of Absent GUDMAP:14314
TS22: female reproductive system Absent GUDMAP:14314
TS22: reproductive system Absent GUDMAP:14314
TS22: muscle layer of ventral pelvic urethra Absent GUDMAP:14314
TS22: muscle layer of dorsal pelvic urethra Absent GUDMAP:14314
TS22: muscle layer of pelvic urethra Absent GUDMAP:14314
TS22: epithelium of pelvic urethra Absent GUDMAP:14314
TS22: mesenchymal layer of ventral pelvic urethra Present Regionally restricted GUDMAP:14314 Expression present along length of urethra only.
TS22: mesenchymal layer of dorsal pelvic urethra Present Regionally restricted GUDMAP:14314 Strong expression in group of cells located near urogenital sinus. Moderate expression extends along length of urethra only.
TS22: mesenchymal layer of pelvic urethra Present GUDMAP:14314
TS22: pelvic urethra Present GUDMAP:14314
TS22: urethra Present GUDMAP:14314
TS22: urinary system Present GUDMAP:14314
TS22: vasculature of bladder Absent GUDMAP:14314
TS22: adventitia of ventral bladder neck Absent GUDMAP:14314
TS22: adventitia of bladder trigone Absent GUDMAP:14314
TS22: serosa of bladder fundus Absent GUDMAP:14314
TS22: serosa of bladder Absent GUDMAP:14314
TS22: detrusor muscle of ventral bladder neck Absent GUDMAP:14314
TS22: detrusor muscle of bladder trigone Absent GUDMAP:14314
TS22: detrusor muscle of bladder fundus Absent GUDMAP:14314
TS22: detrusor muscle of bladder Absent GUDMAP:14314
TS22: lamina propria of ventral bladder neck Absent GUDMAP:14314
TS22: lamina propria of bladder trigone Absent GUDMAP:14314
TS22: lamina propria of bladder fundus Absent GUDMAP:14314
TS22: lamina propria of bladder Absent GUDMAP:14314
TS22: urothelium of ventral bladder neck Absent GUDMAP:14314
TS22: urothelium of bladder trigone Absent GUDMAP:14314
TS22: urothelium of bladder fundus Absent GUDMAP:14314
TS22: basal cell layer of bladder urothelium Absent GUDMAP:14314
TS22: superficial cell layer of bladder urothelium Absent GUDMAP:14314
TS22: urothelium of bladder Absent GUDMAP:14314
TS22: bladder Absent GUDMAP:14314
Specimen GUDMAP:14315: embryonic day 17.0 (more )
Note: Labeling was visualized using BM purple. The section was also labeled by immunohistochemistry to visualize cadherin 1 in epithelium (red) and actin alpha 2 in smooth muscle (green).
Structure Level Pattern Image Note
TS25: male accessory gland Present GUDMAP:14315
TS25: prostate bud Present GUDMAP:14315
TS25: seminal vesicle Present GUDMAP:14315
TS25: ejaculatory duct Present GUDMAP:14315
TS25: male reproductive system Present GUDMAP:14315
TS25: reproductive system Present GUDMAP:14315
TS25: ductus deferens Present GUDMAP:14315
TS25: epithelium of seminal vesicle Absent GUDMAP:14315
TS25: muscle of seminal vesicle Absent GUDMAP:14315
TS25: serosa of seminal vesicle Absent GUDMAP:14315
TS25: vasculature of seminal vesicle Absent GUDMAP:14315
TS25: epithelium of ductus deferens Absent GUDMAP:14315
TS25: muscle of ductus deferens Absent GUDMAP:14315
TS25: vasculature of ductus deferens Absent GUDMAP:14315
TS25: epithelium of ejaculatory duct Absent GUDMAP:14315
TS25: muscle of ejaculatory duct Absent GUDMAP:14315
TS25: vasculature of ejaculatory duct Absent GUDMAP:14315
TS25: lamina propria of ejaculatory duct Present GUDMAP:14315
TS25: prostate epithelium Absent GUDMAP:14315
TS25: peri-prostatic mesenchyme Present GUDMAP:14315
TS25: presumptive neural crest derivative of pelvic urethra of male Absent GUDMAP:14315
TS25: vasculature of pelvic urethra of male Absent GUDMAP:14315
TS25: muscle layer of ventral pelvic urethra of male Absent GUDMAP:14315
TS25: muscle layer of dorsal pelvic urethra of male Absent GUDMAP:14315
TS25: muscle layer of pelvic urethra of male Absent GUDMAP:14315
TS25: mesenchymal layer of pelvic urethra of male Present GUDMAP:14315
TS25: pelvic urethra of male Present GUDMAP:14315
TS25: urethra of male Present GUDMAP:14315
TS25: urinary system Present GUDMAP:14315
TS25: mesenchymal pad of pelvic urethra of male Present GUDMAP:14315
TS25: muscularis mucosa of ventral pelvic urethra of male Absent GUDMAP:14315
TS25: muscularis mucosa of dorsal pelvic urethra of male Absent GUDMAP:14315
TS25: submucosa of ventral pelvic urethra of male Present Graded GUDMAP:14315
TS25: submucosa of dorsal pelvic urethra of male Present Graded GUDMAP:14315
TS25: lamina propria of dorsal pelvic urethra of male Present GUDMAP:14315
TS25: lamina propria of ventral pelvic urethra of male Present GUDMAP:14315
TS25: mesenchymal layer of dorsal pelvic urethra of male Present GUDMAP:14315
TS25: basal cell layer of ventral pelvic urethra of male Absent GUDMAP:14315
TS25: intermediate cell layer of ventral pelvic urethra of male Absent GUDMAP:14315
TS25: superficial cell layer of ventral pelvic urethra of male Absent GUDMAP:14315
TS25: epithelium of ventral pelvic urethra of male Absent GUDMAP:14315
TS25: basal cell layer of dorsal pelvic urethra of male Absent GUDMAP:14315
TS25: intermediate cell layer of dorsal pelvic urethra of male Absent GUDMAP:14315
TS25: superficial cell layer of dorsal pelvic urethra of male Absent GUDMAP:14315
TS25: epithelium of dorsal pelvic urethra of male Absent GUDMAP:14315
TS25: epithelium of pelvic urethra of male Absent GUDMAP:14315
TS25: mesenchymal layer of ventral pelvic urethra of male Present GUDMAP:14315
Specimen GUDMAP:14316: embryonic day 17.0 (more )
Note: Labeling was visualized using BM purple. The section was also labeled by immunohistochemistry to visualize cadherin 1 in epithelium (red) and actin alpha 2 in smooth muscle (green).
Structure Level Pattern Image Note
TS25: upper vagina Present GUDMAP:14316
TS25: sinovaginal bulb Present GUDMAP:14316
TS25: vagina Present GUDMAP:14316
TS25: female reproductive system Present GUDMAP:14316
TS25: reproductive system Present GUDMAP:14316
TS25: vasculature of upper vagina Absent GUDMAP:14316
TS25: muscle of upper vagina Absent GUDMAP:14316
TS25: epithelium of upper vagina Absent GUDMAP:14316
TS25: vasculature of sinovaginal bulb Absent GUDMAP:14316
TS25: muscle of sinovaginal bulb Absent GUDMAP:14316
TS25: epithelium of sinovaginal bulb Absent GUDMAP:14316
TS25: lamina propria of sinovaginal bulb Present Regionally restricted GUDMAP:14316 Expression only evident on one side near muscle layer.
TS25: lamina propria of upper vagina Present Regionally restricted GUDMAP:14316 Expression only evident distally; not detected proximal to urogenital sinus.
TS25: epithelium of vagina Absent GUDMAP:14316
TS25: muscle of vagina Absent GUDMAP:14316
TS25: developing vasculature of vagina Absent GUDMAP:14316
TS25: presumptive neural crest derivative of pelvic urethra of female Absent GUDMAP:14316
TS25: vasculature of pelvic urethra of female Absent GUDMAP:14316
TS25: muscle layer of pelvic urethra of female Absent GUDMAP:14316
TS25: mesenchymal pad of pelvic urethra of female Absent GUDMAP:14316
TS25: mesenchymal layer of ventral pelvic urethra of female Present GUDMAP:14316
TS25: mesenchymal layer of dorsal pelvic urethra of female Present GUDMAP:14316
TS25: mesenchymal layer of pelvic urethra of female Present GUDMAP:14316
TS25: epithelium of ventral pelvic urethra of female Present GUDMAP:14316
TS25: epithelium of dorsal pelvic urethra of female Present GUDMAP:14316
TS25: epithelium of pelvic urethra of female Present GUDMAP:14316
TS25: pelvic urethra of female Present GUDMAP:14316
TS25: urethra of female Present GUDMAP:14316
TS25: urinary system Present GUDMAP:14316
TS25: muscularis mucosa of ventral pelvic urethra of female Absent GUDMAP:14316
TS25: lamina propria of ventral pelvic urethra of female Absent GUDMAP:14316
TS25: muscularis mucosa of dorsal pelvic urethra of female Absent GUDMAP:14316
TS25: lamina propria of dorsal pelvic urethra of female Absent GUDMAP:14316
TS25: submucosa of dorsal pelvic urethra of female Present Regionally restricted GUDMAP:14316 Expression evident along caudal length of urethra only; not detected along urogenital sinus.
TS25: submucosa of ventral pelvic urethra of female Present GUDMAP:14316
TS25: basal cell layer of ventral pelvic urethra of female Absent GUDMAP:14316
TS25: superficial cell layer of ventral pelvic urethra of female Absent GUDMAP:14316
TS25: basal cell layer of dorsal pelvic urethra of female Absent GUDMAP:14316
TS25: superficial cell layer of dorsal pelvic urethra of female Absent GUDMAP:14316
TS25: intermediate cell layer of ventral pelvic urethra of female Present Regionally restricted GUDMAP:14316 Expression detected in urogenital sinus only.
TS25: intermediate cell layer of dorsal pelvic urethra of female Present Regionally restricted GUDMAP:14316 Expression detected in urogenital sinus only.
TS25: muscle layer of ventral pelvic urethra of female Absent GUDMAP:14316
TS25: muscle layer of dorsal pelvic urethra of female Absent GUDMAP:14316
Specimen GUDMAP:14317: postnatal day 5 (more )
Note: Labeling was visualized using BM purple. The section was also labeled by immunohistochemistry to visualize cadherin 1 in epithelium (red) and actin alpha 2 in smooth muscle (green).
Structure Level Pattern Image Note
TS28: prostate gland Present GUDMAP:14317
TS28: male accessory gland Present GUDMAP:14317
TS28: ejaculatory duct Present GUDMAP:14317
TS28: ductus deferens Present GUDMAP:14317
TS28: seminal vesicle Present GUDMAP:14317
TS28: male reproductive system Present GUDMAP:14317
TS28: reproductive system Present GUDMAP:14317
TS28: vasculature of prostate gland Absent GUDMAP:14317
TS28: prostate epithelium Absent GUDMAP:14317
TS28: ventral prostatic interstitium Present GUDMAP:14317
TS28: ventral prostate gland Present GUDMAP:14317
TS28: lateral prostatic interstitium Present GUDMAP:14317
TS28: lateral prostate gland Present GUDMAP:14317
TS28: dorsal prostatic interstitium Present GUDMAP:14317
TS28: dorsal prostate gland Present GUDMAP:14317
TS28: anterior prostatic interstitium Present GUDMAP:14317
TS28: anterior prostate gland Present GUDMAP:14317
TS28: peri-prostatic mesenchyme Present GUDMAP:14317
TS28: rest of interstitium of ventral prostate Present GUDMAP:14317
TS28: rest of interstitium of lateral prostate Present GUDMAP:14317
TS28: rest of interstitium of dorsal prostate Present GUDMAP:14317
TS28: rest of interstitium of anterior prostate Present GUDMAP:14317
TS28: smooth muscle of ventral prostate Absent GUDMAP:14317
TS28: basal epithelium of ventral prostate Absent GUDMAP:14317
TS28: ventral prostatic epithelium Absent GUDMAP:14317
TS28: smooth muscle of lateral prostate Absent GUDMAP:14317
TS28: basal epithelium of lateral prostate Absent GUDMAP:14317
TS28: lateral prostatic epithelium Absent GUDMAP:14317
TS28: smooth muscle of dorsal prostate Absent GUDMAP:14317
TS28: basal epithelium of dorsal prostate Absent GUDMAP:14317
TS28: dorsal prostatic epithelium Absent GUDMAP:14317
TS28: smooth muscle of anterior prostate Absent GUDMAP:14317
TS28: basal epithelium of anterior prostate Absent GUDMAP:14317
TS28: anterior prostatic epithelium Absent GUDMAP:14317
TS28: epithelium of ejaculatory duct Absent GUDMAP:14317
TS28: muscle of ejaculatory duct Absent GUDMAP:14317
TS28: vasculature of ejaculatory duct Absent GUDMAP:14317
TS28: vasculature of ductus deferens Absent GUDMAP:14317
TS28: serosa of ductus deferens Absent GUDMAP:14317
TS28: longitudinal muscle of ductus deferens Absent GUDMAP:14317
TS28: circular muscle of ductus deferens Absent GUDMAP:14317
TS28: muscle of ductus deferens Absent GUDMAP:14317
TS28: epithelium of ductus deferens Absent GUDMAP:14317
TS28: vasculature of seminal vesicle Absent GUDMAP:14317
TS28: serosa of seminal vesicle Absent GUDMAP:14317
TS28: muscle of seminal vesicle Absent GUDMAP:14317
TS28: epithelium of seminal vesicle Absent GUDMAP:14317
TS28: pelvic urethra of male Absent GUDMAP:14317
TS28: male urethral gland Absent GUDMAP:14317
TS28: vasculature of prostatic urethra Absent GUDMAP:14317
TS28: rhabdosphincter of male Absent GUDMAP:14317
TS28: smooth muscle layer of prostatic urethra Absent GUDMAP:14317
TS28: muscle layer of prostatic urethra Absent GUDMAP:14317
TS28: basal cell layer of prostatic urethra Absent GUDMAP:14317
TS28: intermediate cell layer of prostatic urethra Absent GUDMAP:14317
TS28: superficial cell layer of prostatic urethra Absent GUDMAP:14317
TS28: epithelium of prostatic urethra Absent GUDMAP:14317
TS28: muscularis mucosa of prostatic urethra Absent GUDMAP:14317
TS28: submucosa of prostatic urethra Absent GUDMAP:14317
TS28: prostatic urethra Present GUDMAP:14317
TS28: urethra of male Present GUDMAP:14317
TS28: urinary system Present GUDMAP:14317
TS28: lamina propria of prostatic urethra Present Regionally restricted GUDMAP:14317 Expression evident in dorsal urethra only; not detected in ventral urethra.
TS28: mesenchymal layer of prostatic urethra Present GUDMAP:14317
TS28: vasculature of pelvic urethra of male Absent GUDMAP:14317
TS28: muscle layer of pelvic urethra of male Absent GUDMAP:14317
TS28: submucosa of ventral pelvic urethra of male Absent GUDMAP:14317
TS28: muscularis mucosa of ventral pelvic urethra of male Absent GUDMAP:14317
TS28: lamina propria of ventral pelvic urethra of male Absent GUDMAP:14317
TS28: mesenchymal layer of ventral pelvic urethra of male Absent GUDMAP:14317
TS28: submucosa of dorsal pelvic urethra of male Absent GUDMAP:14317
TS28: muscularis mucosa of dorsal pelvic urethra of male Absent GUDMAP:14317
TS28: lamina propria of dorsal pelvic urethra of male Absent GUDMAP:14317
TS28: mesenchymal layer of dorsal pelvic urethra of male Absent GUDMAP:14317
TS28: mesenchymal layer of pelvic urethra of male Absent GUDMAP:14317
TS28: basal cell layer of ventral pelvic urethra of male Absent GUDMAP:14317
TS28: intermediate cell layer of ventral pelvic urethra of male Absent GUDMAP:14317
TS28: superficial cell layer of ventral pelvic urethra of male Absent GUDMAP:14317
TS28: epithelium of ventral pelvic urethra of male Absent GUDMAP:14317
TS28: basal cell layer of dorsal pelvic urethra of male Absent GUDMAP:14317
TS28: intermediate cell layer of dorsal pelvic urethra of male Absent GUDMAP:14317
TS28: superficial cell layer of dorsal pelvic urethra of male Absent GUDMAP:14317
TS28: epithelium of dorsal pelvic urethra of male Absent GUDMAP:14317
TS28: epithelium of pelvic urethra of male Absent GUDMAP:14317
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04/23/2024
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