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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5541808
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: RIKEN clone 9430085M16 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:13714: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: male reproductive system Present GUDMAP:13714
TS23: genital tubercle of male Present GUDMAP:13714
TS23: scrotal swelling Present GUDMAP:13714
TS23: male external genitalia Present GUDMAP:13714
TS23: epithelium of phallic urethra of male Present Regionally restricted GUDMAP:13714 Weak expression is detected in a small portion of the urethral epithelium of male closest to the opening. Expression is not detected in the phallic urethral epithelium at the base of the external genitalia. The distal urethral epithelium was not present in any of the sections examined.
TS23: urethral tube epithelium of male Present Regionally restricted GUDMAP:13714
TS23: glans of male genital tubercle Present GUDMAP:13714
TS23: skin of glans of male genital tubercle Present GUDMAP:13714
TS23: mesenchyme of glans of male genital tubercle Present Regionally restricted GUDMAP:13714 distal expression; Strong expression is detected in only a small region of the mesenchyme of the glans of the male at the very distal tip.
TS23: preputial swelling of male Present GUDMAP:13714
TS23: skin of male preputial swelling Present GUDMAP:13714
TS23: scrotal swelling skin Present Regionally restricted GUDMAP:13714 Expression detected in a subset of the surface epithelium both regionally (a portion closest to the opening of the urethral epithelium and the portion closest to the hindgut) and both of the sub regions show expression in the basal layer of the surface epithelium.
TS23: mesenchyme of scrotal swelling Present Regionally restricted GUDMAP:13714 Regional mesenchymal expression in two small regions either side of the surface epithelium at the base of the labioscrotal swelling where it meets the hindgut.
TS23: nephric duct of male, rest of Absent GUDMAP:13714
TS23: degenerating rest of paramesonephric duct of male Absent GUDMAP:13714
TS23: epithelium of degenerating rest of paramesonephric duct of male Absent GUDMAP:13714
TS23: mesenchyme of degenerating rest of paramesonephric duct of male Absent GUDMAP:13714
TS23: epithelium of nephric duct of male Absent GUDMAP:13714
TS23: mesenchyme of nephric duct of male Absent GUDMAP:13714
TS23: mesenchyme of male preputial swelling Absent GUDMAP:13714
TS23: developing vasculature of male genital tubercle Ambiguous GUDMAP:13714 Uncertain weak expression associated with the large artery of the genital tubercle.
TS23: proximal urethral meatus of male Present GUDMAP:13714

Specimen GUDMAP:13715: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:13715
TS23: bladder Present GUDMAP:13715
TS23: lamina propria of bladder Present GUDMAP:13715
TS23: detrusor muscle of bladder Present GUDMAP:13715
TS23: urothelium of bladder Absent GUDMAP:13715
TS23: serosa of bladder Ambiguous GUDMAP:13715
TS23: adventitia of bladder Ambiguous GUDMAP:13715
TS23: urethra of male Present GUDMAP:13715
TS23: pelvic urethra of male Present GUDMAP:13715
TS23: muscle layer of pelvic urethra of male Present GUDMAP:13715
TS23: urethral plate epithelium of male Present Regionally restricted GUDMAP:13715 Weak expression detected in a portion of the phallic urethral epithelium closest to the opening.
TS23: phallic urethra of male Present GUDMAP:13715
TS23: epithelium of pelvic urethra of male Absent GUDMAP:13715
TS23: mesenchymal layer of pelvic urethra of male Absent GUDMAP:13715

Specimen GUDMAP:13716: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: female reproductive system Present GUDMAP:13716
TS23: genital tubercle of female Present GUDMAP:13716
TS23: labial swelling Present GUDMAP:13716
TS23: female external genitalia Present GUDMAP:13716
TS23: preputial swelling of female Present GUDMAP:13716
TS23: skin of female preputial swelling Present GUDMAP:13716
TS23: glans of female genital tubercle Present GUDMAP:13716
TS23: mesenchyme of glans of female genital tubercle Present Regionally restricted GUDMAP:13716 distal expression; Weak expression in a portion of the distal mesenchyme only. All other mesenchymal layers of the genital tubercle are absent.
TS23: genital tubercle mesenchyme of female Present GUDMAP:13716
TS23: labial swelling skin Present Regionally restricted GUDMAP:13716 Regional expression in the basal layer of the surface epithelium.
TS23: mesenchyme of labial swelling Present Regionally restricted GUDMAP:13716 Regional mesenchymal expression in two regions either side of the surface epithelium at the base of the labioscrotal swelling where it meets the hindgut.
TS23: nephric duct of female, rest of Absent GUDMAP:13716
TS23: paramesonephric duct of female, rest of Absent GUDMAP:13716
TS23: epithelium of rest of paramesonephric duct of female Absent GUDMAP:13716
TS23: mesenchyme of rest of paramesonephric duct of female Absent GUDMAP:13716
TS23: epithelium of nephric duct of female Absent GUDMAP:13716
TS23: mesenchyme of nephric duct of female Absent GUDMAP:13716
TS23: mesenchyme of female preputial swelling Absent GUDMAP:13716

Specimen GUDMAP:13717: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:13717
TS23: bladder Present GUDMAP:13717
TS23: lamina propria of bladder Present GUDMAP:13717
TS23: detrusor muscle of bladder Present GUDMAP:13717
TS23: urothelium of bladder Absent GUDMAP:13717
TS23: serosa of bladder Ambiguous GUDMAP:13717
TS23: adventitia of bladder Ambiguous GUDMAP:13717
TS23: urethra of female Present GUDMAP:13717
TS23: pelvic urethra of female Present GUDMAP:13717
TS23: muscle layer of pelvic urethra of female Present GUDMAP:13717
TS23: epithelium of pelvic urethra of female Absent GUDMAP:13717
TS23: mesenchymal layer of pelvic urethra of female Absent GUDMAP:13717


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory