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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5541789
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Probe: RIKEN clone G630030I18 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:13661: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: male reproductive system Present GUDMAP:13661
TS23: genital tubercle of male Present GUDMAP:13661 Graded expression within the mesenchyme of the external genitalia with strongest expression in the glans and stronger expression in a band down the center of the genitalia.
TS23: scrotal swelling Present GUDMAP:13661
TS23: glans of male genital tubercle Present GUDMAP:13661
TS23: skin of glans of male genital tubercle Present GUDMAP:13661
TS23: mesenchyme of glans of male genital tubercle Present GUDMAP:13661
TS23: preputial swelling of male Present GUDMAP:13661
TS23: mesenchyme of male preputial swelling Present GUDMAP:13661
TS23: mesenchyme of scrotal swelling Present GUDMAP:13661
TS23: scrotal swelling skin Absent GUDMAP:13661
TS23: developing vasculature of male genital tubercle Absent GUDMAP:13661
TS23: urethral tube epithelium of male Absent GUDMAP:13661
TS23: skin of male preputial swelling Ambiguous GUDMAP:13661
TS23: urethral plate epithelium of male Present GUDMAP:13661
TS23: epithelium of phallic urethra of male Present GUDMAP:13661
TS23: degenerating rest of paramesonephric duct of male Absent GUDMAP:13661
TS23: epithelium of degenerating rest of paramesonephric duct of male Absent GUDMAP:13661
TS23: mesenchyme of degenerating rest of paramesonephric duct of male Absent GUDMAP:13661
TS23: nephric duct of male, rest of Absent GUDMAP:13661
TS23: epithelium of nephric duct of male Absent GUDMAP:13661
TS23: mesenchyme of nephric duct of male Absent GUDMAP:13661

Specimen GUDMAP:13662: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:13662 Strong expression in presumptive neural crest derivatives.
TS23: urothelium of bladder Absent GUDMAP:13662
TS23: lamina propria of bladder Absent GUDMAP:13662
TS23: detrusor muscle of bladder Absent GUDMAP:13662
TS23: serosa of bladder Absent GUDMAP:13662
TS23: adventitia of bladder Absent GUDMAP:13662
TS23: vasculature of bladder Absent GUDMAP:13662
TS23: nerve of bladder Ambiguous GUDMAP:13662 Strong expression in presumptive neural crest derivatives.
TS23: ureter Present GUDMAP:13662
TS23: ureteral mesenchyme Present GUDMAP:13662
TS23: ureteral mesenchyme subepithelial layer Present GUDMAP:13662
TS23: urothelium of ureter Absent GUDMAP:13662
TS23: urethra of male Present GUDMAP:13662
TS23: pelvic urethra of male Present GUDMAP:13662
TS23: mesenchymal layer of pelvic urethra of male Present GUDMAP:13662
TS23: phallic urethra of male Present GUDMAP:13662
TS23: urethral fold of male Present GUDMAP:13662
TS23: epithelium of pelvic urethra of male Present GUDMAP:13662 Weak expression in pelvic urethra closest to bladder but likely absent closer to the phallic urethra.
TS23: muscle layer of pelvic urethra of male Present GUDMAP:13662
TS23: nerve of pelvic urethra of male Ambiguous GUDMAP:13662 Strong expression in presumptive neural crest derivatives.
TS23: urethral plate epithelium of male Absent GUDMAP:13662
TS23: pelvic ganglion Present GUDMAP:13662 Strong expression in presumptive neural crest derivatives.

Specimen GUDMAP:13663: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: female reproductive system Present GUDMAP:13663
TS23: genital tubercle of female Present GUDMAP:13663 Graded expression within the mesenchyme of the external genitalia with strongest expression in the distal genital tubercle and stronger expression in a band down the center of the genitalia.
TS23: labial swelling Present GUDMAP:13663
TS23: female external genitalia Present GUDMAP:13663
TS23: glans of female genital tubercle Present GUDMAP:13663
TS23: genital tubercle mesenchyme of female Present GUDMAP:13663
TS23: mesenchyme of glans of female genital tubercle Present GUDMAP:13663
TS23: preputial swelling of female Present GUDMAP:13663
TS23: mesenchyme of female preputial swelling Present GUDMAP:13663
TS23: skin of female preputial swelling Present GUDMAP:13663
TS23: mesenchyme of labial swelling Present GUDMAP:13663
TS23: labial swelling skin Ambiguous GUDMAP:13663
TS23: epithelium of phallic urethra of female Ambiguous GUDMAP:13663

Specimen GUDMAP:13664: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:13664 Strong expression in presumptive neural crest derivatives.
TS23: urothelium of bladder Absent GUDMAP:13664
TS23: lamina propria of bladder Absent GUDMAP:13664
TS23: detrusor muscle of bladder Absent GUDMAP:13664
TS23: serosa of bladder Absent GUDMAP:13664
TS23: adventitia of bladder Absent GUDMAP:13664
TS23: vasculature of bladder Absent GUDMAP:13664
TS23: nerve of bladder Ambiguous GUDMAP:13664 Strong expression in presumptive neural crest derivatives.
TS23: urethra of female Present GUDMAP:13664
TS23: pelvic urethra of female Present GUDMAP:13664
TS23: epithelium of pelvic urethra of female Present GUDMAP:13664
TS23: mesenchymal layer of pelvic urethra of female Present GUDMAP:13664
TS23: muscle layer of pelvic urethra of female Present GUDMAP:13664
TS23: nerve of pelvic urethra of female Ambiguous GUDMAP:13664 Strong expression in presumptive neural crest derivatives.
TS23: pelvic ganglion Present GUDMAP:13664 Strong expression in presumptive neural crest derivatives.
TS23: phallic urethra of female Present GUDMAP:13664
TS23: urethral fold of female Present GUDMAP:13664
TS23: urethral plate epithelium of female Ambiguous GUDMAP:13664


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory