Slc22a6 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type:	RNA in situ
MGI Accession ID:	MGI:5540903
Gene symbol:	Slc22a6
Gene name:	solute carrier family 22 (organic anion transporter), member 6

Probe:	RIKEN clone 9630022J22 subclone
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

GUDMAP:9116 ©

Specimen GUDMAP:9116: embryonic day 15.5 (more

)
Note: Labeling was visualized using BM purple.

Structure	Level	Pattern	Image	Note
TS23: urinary system	Present	Regionally restricted	GUDMAP:9116
TS23: metanephros	Present	Regionally restricted	GUDMAP:9116
TS23: renal cortex	Present	Regionally restricted	GUDMAP:9116
TS23: cortical renal tubule	Present	Regionally restricted	GUDMAP:9116
TS23: cortical early proximal tubule	Present	Regionally restricted	GUDMAP:9116	weak expression in presumptive S1 segment of early proximal tubule at urinary pole of maturing nephrons
TS23: maturing nephron	Present	Regionally restricted	GUDMAP:9116
TS23: renal capsule	Absent		GUDMAP:9116
TS23: nephrogenic zone	Absent		GUDMAP:9116
TS23: nephrogenic interstitium	Absent		GUDMAP:9116
TS23: cap mesenchyme	Absent		GUDMAP:9116
TS23: pretubular aggregate	Absent		GUDMAP:9116
TS23: ureteric tip	Absent		GUDMAP:9116
TS23: ureteric tree terminal branch excluding tip itself	Absent		GUDMAP:9116
TS23: renal vesicle	Absent		GUDMAP:9116
TS23: comma-shaped body	Absent		GUDMAP:9116
TS23: upper limb of comma-shaped body	Absent		GUDMAP:9116
TS23: lower limb of comma-shaped body	Absent		GUDMAP:9116
TS23: s-shaped body	Absent		GUDMAP:9116
TS23: renal connecting tubule of s-shaped body	Absent		GUDMAP:9116
TS23: distal segment of s-shaped body	Absent		GUDMAP:9116
TS23: medial segment of s-shaped body	Absent		GUDMAP:9116
TS23: proximal segment of s-shaped body	Absent		GUDMAP:9116
TS23: visceral epithelium of s-shaped body	Absent		GUDMAP:9116
TS23: parietal epithelium of s-shaped body	Absent		GUDMAP:9116
TS23: capillary loop renal corpuscle	Absent		GUDMAP:9116
TS23: visceral epithelium of capillary loop renal corpuscle	Absent		GUDMAP:9116
TS23: parietal epithelium of capillary loop renal corpuscle	Absent		GUDMAP:9116
TS23: presumptive mesangium of capillary loop renal corpuscle	Absent		GUDMAP:9116
TS23: presumptive endothelium of capillary loop renal corpuscle	Absent		GUDMAP:9116
TS23: associated interstitium of capillary loop renal corpuscle	Absent		GUDMAP:9116
TS23: maturing renal corpuscle	Absent		GUDMAP:9116
TS23: maturing glomerular tuft	Absent		GUDMAP:9116
TS23: glomerular capillary system of maturing glomerular tuft	Absent		GUDMAP:9116
TS23: glomerular basement membrane of maturing renal corpuscle	Absent		GUDMAP:9116
TS23: glomerular mesangium of maturing glomerular tuft	Absent		GUDMAP:9116
TS23: visceral epithelium of maturing renal corpuscle	Absent		GUDMAP:9116
TS23: Bowman's capsule of maturing renal corpuscle	Absent		GUDMAP:9116
TS23: parietal epithelium of maturing renal corpuscle	Absent		GUDMAP:9116
TS23: glomerular mesangium of maturing renal corpuscle	Absent		GUDMAP:9116
TS23: juxtaglomerular arteriole	Absent		GUDMAP:9116
TS23: anlage of loop of Henle of cortical renal tubule	Absent		GUDMAP:9116
TS23: renal connecting tubule	Absent		GUDMAP:9116
TS23: cortical collecting duct	Absent		GUDMAP:9116
TS23: renal cortical interstitium	Absent		GUDMAP:9116
TS23: renal cortical vasculature	Absent		GUDMAP:9116
TS23: renal cortical arterial system	Absent		GUDMAP:9116
TS23: renal cortical venous system	Absent		GUDMAP:9116
TS23: renal cortical capillary	Absent		GUDMAP:9116
TS23: renal medulla	Absent		GUDMAP:9116
TS23: immature loop of Henle	Absent		GUDMAP:9116
TS23: straight limb of immature loop of Henle	Absent		GUDMAP:9116
TS23: bend of immature loop of Henle	Absent		GUDMAP:9116
TS23: renal medullary interstitium	Absent		GUDMAP:9116
TS23: renal medullary vasculature	Absent		GUDMAP:9116
TS23: renal medullary arterial system	Absent		GUDMAP:9116
TS23: renal medullary venous system	Absent		GUDMAP:9116
TS23: renal medullary capillary	Absent		GUDMAP:9116
TS23: medullary collecting duct	Absent		GUDMAP:9116
TS23: renal calyx	Absent		GUDMAP:9116
TS23: renal pelvis	Absent		GUDMAP:9116
TS23: pelvic urothelial lining	Absent		GUDMAP:9116
TS23: pelvic smooth muscle	Absent		GUDMAP:9116
TS23: perihilar interstitium	Absent		GUDMAP:9116
TS23: developing capillary loop stage nephron group	Absent		GUDMAP:9116
TS23: collecting duct	Absent		GUDMAP:9116
TS23: renal interstitium	Absent		GUDMAP:9116
TS23: renal vasculature	Absent		GUDMAP:9116
TS23: early nephron	Absent		GUDMAP:9116
TS23: cortical early distal tubule	Ambiguous		GUDMAP:9116	note it is very hard to distinguish distal tubule at this stage
TS23: early proximal tubule of maturing nephron	Present		GUDMAP:9116
TS23: cortical renal tubule of maturing nephron group	Present		GUDMAP:9116
TS23: distal renal vesicle	Absent		GUDMAP:9116
TS23: proximal renal vesicle	Absent		GUDMAP:9116
TS23: renal connecting segment of renal vesicle	Absent		GUDMAP:9116
TS23: renal connecting segment of comma-shaped body	Absent		GUDMAP:9116
TS23: cortical renal tubule of capillary loop nephron group	Absent		GUDMAP:9116
TS23: early proximal tubule of capillary loop nephron	Absent		GUDMAP:9116
TS23: early distal tubule of capillary loop nephron	Absent		GUDMAP:9116
TS23: renal connecting tubule of capillary loop nephron	Absent		GUDMAP:9116
TS23: renal connecting tubule of maturing nephron	Absent		GUDMAP:9116
TS23: early distal tubule of maturing nephron	Ambiguous		GUDMAP:9116

GUDMAP:9117 ©

Specimen GUDMAP:9117: embryonic day 15.5 (more

)
Note: Labeling was visualized using BM purple.

Structure	Level	Image
TS23: ureter	Absent	GUDMAP:9117
TS23: urothelium of ureter	Absent	GUDMAP:9117
TS23: ureteral mesenchyme	Absent	GUDMAP:9117
TS23: ureteral mesenchyme subepithelial layer	Absent	GUDMAP:9117
TS23: ureteral smooth muscle layer	Absent	GUDMAP:9117
TS23: ureteral mesenchyme outer layer	Absent	GUDMAP:9117

GUDMAP:13939 ©

Specimen GUDMAP:13939: postnatal adult (more

)
Note: This animal was sexually mature. Labeling was visualized using BM purple. Moderate expression was seen with the low level expression control (Shh). Thus, low levels of mRNA expression should be detectable in this experiment.

Structure	Level	Pattern	Image	Note
TS28: urinary system	Present		GUDMAP:13939
TS28: metanephros	Present		GUDMAP:13939
TS28: renal cortex	Present		GUDMAP:13939
TS28: cortical renal tubule	Present		GUDMAP:13939
TS28: renal proximal tubule	Present	Regionally restricted	GUDMAP:13939
TS28: renal proximal convoluted tubule	Present	Regionally restricted	GUDMAP:13939	Expression in a subset of proximal convoluted tubules including segment 2 and possibly a subregion of segment 1. Absent from the portion of segment 1 immediately adjacent to the renal corpuscle at the urinary pole.
TS28: segment 2 of proximal tubule	Present		GUDMAP:13939
TS28: segment 1 of proximal tubule	Ambiguous		GUDMAP:13939
TS28: proximal straight tubule, cortical portion	Absent		GUDMAP:13939
TS28: renal distal tubule	Absent		GUDMAP:13939
TS28: renal connecting tubule	Absent		GUDMAP:13939
TS28: cortical collecting duct	Absent		GUDMAP:13939
TS28: renal cortical vasculature	Absent		GUDMAP:13939
TS28: renal cortical interstitium	Absent		GUDMAP:13939
TS28: renal medulla	Absent		GUDMAP:13939
TS28: renal pelvis	Absent		GUDMAP:13939
TS28: mature renal corpuscle	Absent		GUDMAP:13939

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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