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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540704
Gene symbol: Wnt4
Gene name: wingless-type MMTV integration site family, member 4
Probe: RIKEN clone 2810012H16 subclone 2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:7155: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: mesonephric tubule Present GUDMAP:7155
TS17: nephric duct, mesonephric portion Present GUDMAP:7155
TS17: mesonephros Present GUDMAP:7155 signal can be seen in the entire length of
TS17: gonad primordium Present GUDMAP:7155
TS17: metanephric mesenchyme Absent GUDMAP:7155
TS17: nephric duct, metanephric portion Absent GUDMAP:7155

Specimen GUDMAP:7156: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: nephrogenic zone Present GUDMAP:7156
TS23: pretubular aggregate Present GUDMAP:7156
TS23: renal cortex Present GUDMAP:7156
TS23: renal vesicle Present GUDMAP:7156
TS23: comma-shaped body Present GUDMAP:7156
TS23: upper limb of comma-shaped body Present GUDMAP:7156
TS23: s-shaped body Present GUDMAP:7156
TS23: medial segment of s-shaped body Present GUDMAP:7156
TS23: lower limb of comma-shaped body Present GUDMAP:7156
TS23: cortical collecting duct Present GUDMAP:7156
TS23: renal cortical interstitium Present GUDMAP:7156 restricted to a subset of cells immediately surrounding the collecting ducts for Wnt4 RNA
TS23: medullary collecting duct Present GUDMAP:7156
TS23: renal medullary interstitium Present GUDMAP:7156 restricted to a subset of cells immediately surrounding the collecting ducts for Wnt4 RNA
TS23: renal pelvis Present GUDMAP:7156
TS23: pelvic urothelial lining Present GUDMAP:7156
TS23: ureter Present GUDMAP:7156
TS23: urothelium of ureter Present GUDMAP:7156 weak signal in proximal ureter located next to metanephros
TS23: ureteric tip Absent GUDMAP:7156
TS23: capillary loop renal corpuscle Absent GUDMAP:7156
TS23: maturing renal corpuscle Absent GUDMAP:7156

Specimen GUDMAP:7157: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: mesonephros of male Present GUDMAP:7157
TS20: mesonephric mesenchyme of male Present GUDMAP:7157 Wnt4 signal was strongest at the junction where it contacts the ovary and two lines of signal in the mesonephric mesenchyme running medial to and parallel to the nephric duct and paramesonephric duct.
TS20: testis Absent GUDMAP:7157

Specimen GUDMAP:7158: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: mesonephros of female Present GUDMAP:7158
TS20: mesonephric mesenchyme of female Present GUDMAP:7158 Wnt4 signal was strongest at the junction where it contacts the ovary and two lines of signal in the mesonephric mesenchyme running medial to and parallel to the nephric duct and paramesonephric duct.
TS20: ovary Present GUDMAP:7158
TS20: mesenchymal stroma of ovary Present GUDMAP:7158

Specimen GUDMAP:7159: embryonic day 13.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS21: metanephros Present GUDMAP:7159
TS21: nephrogenic zone Present GUDMAP:7159
TS21: early nephron Present GUDMAP:7159
TS21: comma-shaped body Present GUDMAP:7159
TS21: nephric duct of male, rest of Present GUDMAP:7159
TS21: mesonephros of male Present GUDMAP:7159 signal strongest immediately surrounding the nephric duct epithelium
TS21: nephric duct of male, mesonephric portion Present GUDMAP:7159
TS21: primitive bladder Present GUDMAP:7159 signal restricted to the epithelium of the bladder
TS21: mesonephric mesenchyme of male Present GUDMAP:7159
TS21: paramesonephric duct of male, mesonephric portion Present GUDMAP:7159 restricted to the rostral tip
TS21: paramesonephric duct of male, rest of Absent GUDMAP:7159
TS21: testis Absent GUDMAP:7159

Specimen GUDMAP:7160: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: metanephros Present GUDMAP:7160
TS20: early nephron Present GUDMAP:7160
TS20: primitive bladder Present GUDMAP:7160

Specimen GUDMAP:7466: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:7466
TS23: urothelium of bladder Present GUDMAP:7466
TS23: superficial cell layer of ureter Present GUDMAP:7466
TS23: intermediate cell layer of ureter Present GUDMAP:7466
TS23: basal cell layer of ureter Present GUDMAP:7466

Specimen GUDMAP:8208: embryonic day 15.5 (more )
Note: Double labeled: blue - Wnt4 RNA; brown-orange - Calb1 protein (assay MGI:5548301; GUDMAP:8199).
Structure Level Pattern Image Note
TS23: metanephros Present Regionally restricted GUDMAP:8208
TS23: nephrogenic zone Present GUDMAP:8208
TS23: pretubular aggregate Present GUDMAP:8208
TS23: renal cortex Present GUDMAP:8208
TS23: renal vesicle Present Regionally restricted GUDMAP:8208
TS23: comma-shaped body Present GUDMAP:8208
TS23: upper limb of comma-shaped body Present GUDMAP:8208
TS23: lower limb of comma-shaped body Present GUDMAP:8208
TS23: s-shaped body Present GUDMAP:8208
TS23: medial segment of s-shaped body Present GUDMAP:8208
TS23: proximal segment of s-shaped body Present Regionally restricted GUDMAP:8208
TS23: cortical collecting duct Present Regionally restricted GUDMAP:8208
TS23: renal cortical interstitium Present Regionally restricted GUDMAP:8208
TS23: medullary collecting duct Present Regionally restricted GUDMAP:8208
TS23: renal medullary interstitium Present Regionally restricted GUDMAP:8208
TS23: renal pelvis Present GUDMAP:8208
TS23: pelvic urothelial lining Present GUDMAP:8208
TS23: ureter Present GUDMAP:8208
TS23: urothelium of ureter Present GUDMAP:8208
TS23: early nephron Present GUDMAP:8208
TS23: ureteric tip Absent GUDMAP:8208
TS23: nephrogenic interstitium Absent GUDMAP:8208
TS23: cap mesenchyme Absent GUDMAP:8208
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:8208
TS23: capillary loop renal corpuscle Absent GUDMAP:8208
TS23: maturing renal corpuscle Absent GUDMAP:8208
TS23: renal cortical vasculature Absent GUDMAP:8208
TS23: cortical renal tubule Absent GUDMAP:8208
TS23: renal medullary vasculature Absent GUDMAP:8208
TS23: immature loop of Henle Absent GUDMAP:8208
TS23: pelvic smooth muscle Absent GUDMAP:8208
TS23: perihilar interstitium Absent GUDMAP:8208
TS23: distal segment of s-shaped body Absent GUDMAP:8208
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:8208

Specimen GUDMAP:8209: embryonic day 15.5 (more )
Note: Double labeled: blue - Wnt4 RNA; brown-orange - Wt1 protein (assay MGI:5548311; GUDMAP:8200).
Structure Level Pattern Image Note
TS23: metanephros Present Regionally restricted GUDMAP:8209
TS23: nephrogenic zone Present GUDMAP:8209
TS23: pretubular aggregate Present GUDMAP:8209
TS23: renal cortex Present GUDMAP:8209
TS23: renal vesicle Present Regionally restricted GUDMAP:8209
TS23: comma-shaped body Present GUDMAP:8209
TS23: upper limb of comma-shaped body Present GUDMAP:8209
TS23: lower limb of comma-shaped body Present GUDMAP:8209
TS23: s-shaped body Present GUDMAP:8209
TS23: medial segment of s-shaped body Present GUDMAP:8209
TS23: proximal segment of s-shaped body Present Regionally restricted GUDMAP:8209 Wnt4 signal in a subset of cells closest to medial segment which overlap with W1 protein
TS23: cortical collecting duct Present Regionally restricted GUDMAP:8209
TS23: renal cortical interstitium Present Regionally restricted GUDMAP:8209 restricted to a subset of cells immediately surrounding the collecting ducts
TS23: medullary collecting duct Present Regionally restricted GUDMAP:8209
TS23: renal medullary interstitium Present Regionally restricted GUDMAP:8209 restricted to a subset of cells immediately surrounding the collecting ducts
TS23: renal pelvis Present GUDMAP:8209
TS23: pelvic urothelial lining Present GUDMAP:8209
TS23: ureter Present Regionally restricted GUDMAP:8209
TS23: urothelium of ureter Present GUDMAP:8209 weak signal in urothelium of proximal ureter
TS23: early nephron Present GUDMAP:8209
TS23: ureteric tip Absent GUDMAP:8209
TS23: nephrogenic interstitium Absent GUDMAP:8209
TS23: cap mesenchyme Absent GUDMAP:8209
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:8209
TS23: capillary loop renal corpuscle Absent GUDMAP:8209
TS23: maturing renal corpuscle Absent GUDMAP:8209
TS23: renal cortical vasculature Absent GUDMAP:8209
TS23: cortical renal tubule Absent GUDMAP:8209
TS23: renal medullary vasculature Absent GUDMAP:8209
TS23: immature loop of Henle Absent GUDMAP:8209
TS23: pelvic smooth muscle Absent GUDMAP:8209
TS23: perihilar interstitium Absent GUDMAP:8209
TS23: distal segment of s-shaped body Absent GUDMAP:8209
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:8209

Specimen GUDMAP:13629: postnatal day 2 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urothelium of bladder Present GUDMAP:13629
TS27: bladder Present GUDMAP:13629
TS27: urinary system Present GUDMAP:13629
TS27: nerve of bladder Absent GUDMAP:13629
TS27: vasculature of bladder Absent GUDMAP:13629
TS27: adventitia of bladder Absent GUDMAP:13629
TS27: serosa of bladder Absent GUDMAP:13629
TS27: detrusor muscle of bladder Absent GUDMAP:13629
TS27: lamina propria of bladder Absent GUDMAP:13629

Specimen GUDMAP:13784: embryonic day 15.0 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS23: urothelium of bladder Present GUDMAP:13784
TS23: urethra of male Present GUDMAP:13784
TS23: epithelium of pelvic urethra of male Present GUDMAP:13784
TS23: urethral plate epithelium of male Present GUDMAP:13784

Specimen GUDMAP:13785: embryonic day 13.0 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urothelium of primitive bladder Present GUDMAP:13785
TS21: pelvic urethra Present GUDMAP:13785
TS21: urethral plate Present GUDMAP:13785
TS21: phallic urethra Present GUDMAP:13785

Specimen GUDMAP:14081: postnatal day 0 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urinary system Present GUDMAP:14081
TS27: metanephros Present GUDMAP:14081
TS27: renal cortex Present GUDMAP:14081
TS27: renal vesicle Present GUDMAP:14081
TS27: s-shaped body Present GUDMAP:14081
TS27: pretubular aggregate Present GUDMAP:14081
TS27: nephrogenic zone Present GUDMAP:14081
TS27: renal medulla Present GUDMAP:14081
TS27: renal medullary interstitium Present GUDMAP:14081
TS27: outer renal medulla Present GUDMAP:14081
TS27: outer medullary interstitium Present GUDMAP:14081
TS27: inner renal medulla Present GUDMAP:14081
TS27: inner medullary interstitium Present GUDMAP:14081
TS27: distal renal vesicle Present GUDMAP:14081
TS27: proximal renal vesicle Present GUDMAP:14081
TS27: medial segment of s-shaped body Present GUDMAP:14081
TS27: renal connecting segment of renal vesicle Absent GUDMAP:14081
TS27: ureteric tip Absent GUDMAP:14081
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14081
TS27: cap mesenchyme Absent GUDMAP:14081
TS27: nephrogenic interstitium Absent GUDMAP:14081
TS27: capillary loop renal corpuscle Absent GUDMAP:14081
TS27: maturing renal corpuscle Absent GUDMAP:14081
TS27: mature renal corpuscle Absent GUDMAP:14081
TS27: cortical renal tubule Absent GUDMAP:14081
TS27: cortical collecting duct Absent GUDMAP:14081
TS27: renal cortical interstitium Absent GUDMAP:14081
TS27: renal cortical vasculature Absent GUDMAP:14081
TS27: loop of Henle, outer medullary portion Absent GUDMAP:14081
TS27: outer medullary collecting duct Absent GUDMAP:14081
TS27: loop of Henle, inner medullary portion Absent GUDMAP:14081
TS27: inner medullary collecting duct Absent GUDMAP:14081
TS27: renal medullary vasculature Absent GUDMAP:14081
TS27: renal pelvis Absent GUDMAP:14081

Specimen GUDMAP:14082: postnatal day 2 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urinary system Present GUDMAP:14082
TS27: metanephros Present GUDMAP:14082
TS27: renal cortex Present GUDMAP:14082
TS27: renal vesicle Present GUDMAP:14082
TS27: s-shaped body Present GUDMAP:14082
TS27: pretubular aggregate Present GUDMAP:14082
TS27: nephrogenic zone Present GUDMAP:14082
TS27: renal medulla Present GUDMAP:14082
TS27: renal medullary interstitium Present GUDMAP:14082
TS27: outer renal medulla Present GUDMAP:14082
TS27: outer medullary interstitium Present GUDMAP:14082
TS27: inner renal medulla Present GUDMAP:14082
TS27: inner medullary interstitium Present GUDMAP:14082
TS27: medial segment of s-shaped body Present GUDMAP:14082
TS27: ureteric tip Absent GUDMAP:14082
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14082
TS27: cap mesenchyme Present GUDMAP:14082
TS27: nephrogenic interstitium Absent GUDMAP:14082
TS27: capillary loop renal corpuscle Absent GUDMAP:14082
TS27: maturing renal corpuscle Absent GUDMAP:14082
TS27: mature renal corpuscle Absent GUDMAP:14082
TS27: cortical renal tubule Absent GUDMAP:14082
TS27: cortical collecting duct Absent GUDMAP:14082
TS27: renal cortical interstitium Absent GUDMAP:14082
TS27: renal cortical vasculature Absent GUDMAP:14082
TS27: loop of Henle, outer medullary portion Absent GUDMAP:14082
TS27: outer medullary collecting duct Absent GUDMAP:14082
TS27: loop of Henle, inner medullary portion Absent GUDMAP:14082
TS27: inner medullary collecting duct Present GUDMAP:14082
TS27: renal medullary vasculature Absent GUDMAP:14082
TS27: renal pelvis Absent GUDMAP:14082

Specimen GUDMAP:14083: postnatal day 4 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urinary system Present GUDMAP:14083
TS27: metanephros Present GUDMAP:14083
TS27: renal cortex Present GUDMAP:14083
TS27: renal vesicle Present GUDMAP:14083
TS27: s-shaped body Present GUDMAP:14083
TS27: pretubular aggregate Present GUDMAP:14083
TS27: nephrogenic zone Present GUDMAP:14083
TS27: renal medulla Present GUDMAP:14083
TS27: renal medullary interstitium Present GUDMAP:14083
TS27: outer renal medulla Present GUDMAP:14083
TS27: outer medullary interstitium Present GUDMAP:14083
TS27: inner renal medulla Present GUDMAP:14083
TS27: inner medullary interstitium Present GUDMAP:14083
TS27: medial segment of s-shaped body Present GUDMAP:14083
TS27: ureteric tip Absent GUDMAP:14083
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14083
TS27: nephrogenic interstitium Absent GUDMAP:14083
TS27: capillary loop renal corpuscle Absent GUDMAP:14083
TS27: maturing renal corpuscle Absent GUDMAP:14083
TS27: mature renal corpuscle Absent GUDMAP:14083
TS27: cortical renal tubule Absent GUDMAP:14083
TS27: cortical collecting duct Absent GUDMAP:14083
TS27: renal cortical interstitium Absent GUDMAP:14083
TS27: renal cortical vasculature Absent GUDMAP:14083
TS27: loop of Henle, outer medullary portion Absent GUDMAP:14083
TS27: outer medullary collecting duct Absent GUDMAP:14083
TS27: loop of Henle, inner medullary portion Absent GUDMAP:14083
TS27: inner medullary collecting duct Present Regionally restricted GUDMAP:14083
TS27: renal medullary vasculature Absent GUDMAP:14083
TS27: renal pelvis Absent GUDMAP:14083

Specimen GUDMAP:14084: postnatal day 6 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Present GUDMAP:14084
TS28: urinary system Present GUDMAP:14084
TS28: renal medulla Present GUDMAP:14084
TS28: inner renal medulla Present GUDMAP:14084
TS28: inner medullary interstitium Present GUDMAP:14084
TS28: outer renal medulla Present GUDMAP:14084
TS28: outer medullary interstitium Present GUDMAP:14084
TS28: outer medullary collecting duct Absent GUDMAP:14084
TS28: loop of Henle, inner medullary portion Absent GUDMAP:14084
TS28: inner medullary collecting duct Present Regionally restricted GUDMAP:14084
TS28: renal pelvis Absent GUDMAP:14084
TS28: loop of Henle, outer medullary portion Absent GUDMAP:14084
TS28: renal cortex Absent GUDMAP:14084
TS28: nephrogenic zone Absent GUDMAP:14084

Specimen GUDMAP:14182: embryonic day 17.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS25: metanephros Present GUDMAP:14182
TS25: nephrogenic zone Present GUDMAP:14182
TS25: pretubular aggregate Present GUDMAP:14182
TS25: renal cortex Present GUDMAP:14182
TS25: s-shaped body Present GUDMAP:14182
TS25: comma-shaped body Present GUDMAP:14182
TS25: renal vesicle Present GUDMAP:14182
TS25: medial segment of s-shaped body Present GUDMAP:14182
TS25: renal medulla Present GUDMAP:14182
TS25: outer renal medulla Present GUDMAP:14182
TS25: inner renal medulla Present GUDMAP:14182
TS25: outer medullary interstitium Present GUDMAP:14182
TS25: inner medullary interstitium Present GUDMAP:14182
TS25: nephrogenic interstitium Absent GUDMAP:14182
TS25: cap mesenchyme Absent GUDMAP:14182
TS25: ureteric tip Absent GUDMAP:14182
TS25: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14182
TS25: renal connecting tubule of s-shaped body Absent GUDMAP:14182
TS25: distal segment of s-shaped body Absent GUDMAP:14182
TS25: proximal segment of s-shaped body Absent GUDMAP:14182
TS25: capillary loop renal corpuscle Absent GUDMAP:14182
TS25: maturing renal corpuscle Absent GUDMAP:14182
TS25: mature renal corpuscle Absent GUDMAP:14182
TS25: cortical renal tubule Absent GUDMAP:14182
TS25: cortical collecting duct Absent GUDMAP:14182
TS25: renal cortical vasculature Absent GUDMAP:14182
TS25: loop of Henle, outer medullary portion Absent GUDMAP:14182
TS25: outer medullary collecting duct Absent GUDMAP:14182
TS25: loop of Henle, inner medullary portion Absent GUDMAP:14182
TS25: inner medullary collecting duct Absent GUDMAP:14182
TS25: renal pelvis Present GUDMAP:14182
TS25: ureter Absent GUDMAP:14182
TS25: perihilar interstitium Present GUDMAP:14182
TS25: renal cortical interstitium Present Regionally restricted GUDMAP:14182
TS25: pelvic urothelial lining Absent GUDMAP:14182
TS25: collecting duct Absent GUDMAP:14182
TS25: ureteric trunk Absent GUDMAP:14182
TS25: loop of Henle Absent GUDMAP:14182
TS25: mature nephron Absent GUDMAP:14182
TS25: renal interstitium Present GUDMAP:14182
TS25: developing capillary loop stage nephron group Absent GUDMAP:14182
TS25: maturing nephron Absent GUDMAP:14182
TS25: late tubule Absent GUDMAP:14182
TS25: early tubule Present GUDMAP:14182
TS25: early nephron Present GUDMAP:14182


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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory